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Title of Article Cytotoxic evaluation of rice field frogs (Fejervarya limnocharis) from gold mine area with arsenic contamination 
Date of Acceptance 11 June 2016 
Journal
     Title of Journal The Nucleus 
     Standard SCOPUS 
     Institute of Journal Archana Sharma Foundation of Calcutta 
     ISBN/ISSN 0976-7975 
     Volume 29 
     Issue
     Month December
     Year of Publication 2016 
     Page 181-189 
     Abstract Abstract The objectives of this study were to investigate chromosomal aberrations in rice field frogs (Fejervarya limnocharis) from gold mine area compared to those from non-affected area. Three frogs were collected from each site, and chromosomal aberrations were studied in their bone marrow. Arsenic (As) was also measured in water and sediment from both areas. The average arsenic concentra- tions in samples from the gold mine and the non-affected areas were 0.03 ± 0.003 mg/L and not detected in water and 351.59 ± 5.73 and 1.37 ± 1.07 mg/kg in sediment, respectively. The values in the gold mine were still higher than that allowed by the water and soil quality standards;however, the As concentrations in the samples from the non-affected area were acceptable. The average concentrations of As in the frog samples from the gold mine and the non-affected areas were 0.35 ± 0.33 and 0.07 ± 230.01 mg/kg, respectively, which were both lower than the standard of As contamination in food. The diploid chromosome number of frogs in both areas was 2n = 26, and 26 the percentage of chromosomal breakages in rice field frogs in the gold mine area was higher than in the non- affected area. There were seven types of chromosomal aberrations observed: single chromatid gap, isochromatid gap, single chromatid breaks, deletion, fragmentation, centric fragmentation and polyploidy. The most common chromosomal aberration in the samples from the affected area was the single chromatid gap. The difference in the percentages of chromosomal breakages in rice field frogs from each area was statistically significant (p<0.05). 
     Keyword Cytotoxic evaluation  Chromosomal aberration  Arsenic  Fejervarya limnocharis  Gold mining 
Author
567020067-6 Mr. SOMSAK INTAMAT [Main Author]
Science Doctoral Degree

Reviewing Status มีผู้ประเมินอิสระ 
Status ตีพิมพ์แล้ว 
Level of Publication นานาชาติ 
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