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Publication
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| Research Title |
Toxicity investigation of amanitas wild mushrooms from local market in
Khon Kaen |
| Date of Distribution |
20 June 2018 |
| Conference |
| Title of the Conference |
The 6th International Conference on Biochemistry and Molecular Biology (BMB2018) |
| Organiser |
Chulalongkorn University |
| Conference Place |
Rayong Resort Hotel, Rayong, Thailand |
| Province/State |
Rayong |
| Conference Date |
20 June 2018 |
| To |
22 June 2018 |
| Proceeding Paper |
| Volume |
2018 |
| Issue |
1 |
| Page |
210 |
| Editors/edition/publisher |
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| Abstract |
Mushrooms have high protein content and are recognized as the human diet as well as
versatile medicinal properties. However, some species of mushroom are dangerous because of
their toxicants. In present, cases of people eating toxic mushrooms in Thailand increase
annually, especially in the Northeast. This evidence may result from the inability of consumers
to distinguish edible from inedible species. The most common lethal mushrooms are Amanita
species.Hence, the wild Ra York mushrooms, which are considered as edible mushroom from
a local market in Khon Kaen were preliminary identified by ITS gene amplification.
Ribosomal nucleotide sequencing result indicated that these mushrooms are identical to
Amanita princeps and Amanita hemibapha. Both of wild mushrooms were investigated for the
toxicity effect against the murine macrophage cells (RAW 264.7). The result showed that A.
hemibapha mushroom extract exhibited toxicity against RAW 264.7 cells higher than A.
princeps mushroom extract.Thus, the apoptosis induction of A. hemibapha mushroom extract
was further determined. The result demonstrated that mushroom extract treatment at 25 and
50 μg/ml resulted in the enhancement of late apoptotic cells with dose-dependent manner. This
finding suggested that the A. hemibapha could involve possible risks to human. Therefore,
careful identification is required to ensure safe consumption of wild mushrooms. |
| Author |
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| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
นานาชาติ |
| Type of Proceeding |
Full paper |
| Type of Presentation |
Poster |
| Part of thesis |
true |
| Presentation awarding |
false |
| Attach file |
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| Citation |
0
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Journal Publication
ไทย