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Publication
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| Title of Article |
Antioxidant and anti-nociceptive effects of Phyllanthusamarus on improving exercise recovery in sedentary men: a randomized crossover (double-blind) design |
| Date of Acceptance |
30 August 2014 |
| Journal |
| Title of Journal |
journal of the international society of sports nutrition |
| Standard |
SCOPUS |
| Institute of Journal |
BioMed Central |
| ISBN/ISSN |
- |
| Volume |
2014 |
| Issue |
11 |
| Month |
9 |
| Year of Publication |
2014 |
| Page |
- |
| Abstract |
Background: Phyllanthus amarus (PA) is a herbal plant containing antioxidant compounds that scavenge free
radicals. The reduced oxidative stress may decrease muscle damage leading to early recovery from muscle soreness.
This study aimed to evaluate the effects of PA powder on oxidative stress, muscle damage, leukocyte counts,
inflammation, and muscle soreness after a single bout of high-intensity exercise.
Methods: Twelve men participated in two 3-day phases separated by a 1-week washout in a randomized
double-blinded, crossover design. On day 1, randomly divided participants ingested two capsules of either PA (PA
group) or placebo (PLA group) 20 min before a single bout of cycling at high intensity for 20 min followed by four
capsules (two capsules after lunch and dinner), and six capsules/day for the next 2 days. Blood samples were
collected before, immediately after, and 24 and 48 h after the exercise. Pain threshold was measured at the
mid-thigh on both legs.
Results: Malondialdehyde concentration in the PA group was lower than that in the PLA group (p < 0.05) 48 h after
high-intensity exercise. Vitamin C concentration was greater in the PA than in the PLA group (p < 0.05) immediately
after high-intensity exercise. Pain threshold in both legs in the PA group was higher than in the PLA group 24 and
48 h after high-intensity exercise. There were no significant differences in creatine kinase, leukocyte counts or
inflammation between groups.
Conclusion: Acute PA supplementation reduced oxidative stress and muscle soreness induced by high-intensity
exercise. |
| Keyword |
Herbal plant, Pain threshold, Malondialdehyde, Vitamin C, Muscle damage, Leukocytes, Inflammation |
| Author |
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| Reviewing Status |
มีผู้ประเมินอิสระ |
| Status |
ตีพิมพ์แล้ว |
| Level of Publication |
นานาชาติ |
| citation |
true |
| Part of thesis |
true |
| Attach file |
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| Citation |
6
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Journal Publication
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