| Research Title |
Effects of the Aqueous Extract of Dark Purple Glutinous Rice Variety Luem Pua Tea on Gastrointestinal Movement in Experimental Animals |
| Date of Distribution |
29 May 2015 |
| Conference |
| Title of the Conference |
การประชุมวิชาการสมาคมเภสัชวิทยาแห่งประเทศไทยครั้งที่ 37 |
| Organiser |
สมาคมเภสัชวิทยาแห่งประเทศไทย |
| Conference Place |
โรงแรมสุนีย์ |
| Province/State |
อุบลราชธานี |
| Conference Date |
28 May 2015 |
| To |
30 May 2015 |
| Proceeding Paper |
| Volume |
- |
| Issue |
- |
| Page |
208-212 |
| Editors/edition/publisher |
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| Abstract |
Abstract
Previous reports have indicated many beneficial effects of phenolic compounds from plants on the gastrointestinal tract. The aim of this study is to investigate the effects of aqueous extract of dark purple glutinous rice var. Luem Pua tea on gastrointestinal motility both in vivo and in vitro experiments. Whole gut transit time and intestinal transit rate in mice were measured using the charcoal test. Either water (control), tea extract (equivalent to 2 or 5 g of rice/kg body weight) or ferulic acid (100 mg/kg) was administered orally to the animals. Thirty minutes later, charcoal suspension was administered orally. For whole gut transit time, time after charcoal administration until first observation of defecated charcoal was recorded as a whole gut transit time (min). Intestinal transit rate was determined at 30 min after charcoal administration by measured distance traveled by the charcoal head from the pylorus as well as total length of the small intestine and expressed as % intestinal transit rate. The results showed that the tea extract at both 2 and 5 g/kg, but not ferulic acid, could significantly reduce whole gut transit time in mice. The tea extract at either 2 or 5 g/kg, and ferulic acid could significantly increase intestinal transit rate when compared to the control. In isolated guinea pig ileum, the tea extract induced the contraction of guinea pig ileum in a dose dependent manner while ferulic acid at concentration upto 20 nmol/ml could not. The results suggested that aqueous extract of rice tea from dark purple glutinous rice variety Luem Pua has prokinetic action and might be useful for the treatment of decreasing bowel activity such as constipation.
Keywords: Dark Purple Rice Variety Luem Pua tea, whole gut transit time, intestinal transit rate, isolated ileum
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| Author |
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| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
ชาติ |
| Type of Proceeding |
Full paper |
| Type of Presentation |
Poster |
| Part of thesis |
true |
| Presentation awarding |
true |
| Award Title |
ชมเชย |
| Type of award |
รางวัลด้านวิชาการ วิชาชีพ |
| Organiser |
สมาคมเภสัชวิทยาแห่งประเทศไทย |
| Date of awarding |
29 พฤษภาคม 2558 |
| Attach file |
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| Citation |
0
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Publication
Journal Publication
ไทย