| Research Title |
cytotoxic and antiestrogenic effect of Momordica cochinchinensis extract on MCF-7 breast cancer cells |
| Date of Distribution |
17 September 2012 |
| Conference |
| Title of the Conference |
The 5th Sino-Thai international conference 2012 |
| Organiser |
Guangxi univerasity and KKU |
| Conference Place |
Guangxi univerasity |
| Province/State |
Nanning, CHINA |
| Conference Date |
17 September 2012 |
| To |
20 September 2012 |
| Proceeding Paper |
| Volume |
5 |
| Issue |
- |
| Page |
444 |
| Editors/edition/publisher |
|
| Abstract |
Momordica cochinchinensis (MC) Spreng fruit contains high lycopene content. This study aimed to determine the cytotoxic and antiestrogenic effects of aril extract of MC fruit on MCF-7 breast cancer cells. The aril extract showed cytotoxic effect on MCF-7 cells with IC50 at 277.48±14.17 µg/ml. Its cytotoxic effect increased when co-treatment with tamoxifen. The aril extract demonstrated antiestrogenic activity by inhibiting the proliferation of MCF-7 cells induced by 17β-estradiol in a dose dependent manner. |
| Author |
|
| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
นานาชาติ |
| Type of Proceeding |
Full paper |
| Type of Presentation |
Poster |
| Part of thesis |
true |
| Presentation awarding |
false |
| Attach file |
|
| Citation |
0
|
|
|
Publication
Journal Publication
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