ชื่อบทความ |
Association between Diabetes Mellitus and Fatty Liver Based on Ultrasonography Screening in the World’s Highest Cholangiocarcinoma Incidence Region, Northeast Thailand |
วัน/เดือน/ปี ที่ได้ตอบรับ |
14 พฤษภาคม 2558 |
วารสาร |
ชื่อวารสาร |
Asian pacific Journal of Cancer Prevention |
มาตรฐานของวารสาร |
ISI |
หน่วยงานเจ้าของวารสาร |
UICC-Asia Regional Office/APOCP Coordination |
ISBN/ISSN |
1513-7368 |
ปีที่ |
16 |
ฉบับที่ |
9 |
เดือน |
May |
ปี พ.ศ. ที่พิมพ์ |
2558 |
หน้า |
3931-3936 |
บทคัดย่อ |
Fatty liver disease (FLD) can be a precondition for other liver pathology including cholangiocarcinoma (CCA). Diabetes mellitus (DM) has been suggested in some studies to be a risk factor for FLD as well as cancers, including cholangiocellular carcinoma; however, there are currently very few studies on FLD in DM subjects, although the rate of FLD continues to increase annually. To determine the association between DM and FLD ultrasonographic data were analyzed from the Cholangiocarcinoma Screening and Care Program (CASCAP), in northeast Thailand. DM was reported by the subjects based on the CASCAP health questionnaire. Factors that were associated with FLD were determined by prevalence, odds ratio (ORs) and its 95% confidence intervals (CIs) using multiple logistic regression. There were 45,263 subjects with a mean age of 53.46 (±9.25) years. FLD was found in 36.3% of DM subjects but only in 20.7% of non-DM subjects. The association between DM and FLD was adjusted for all other factors including gender, age, education level, relatives diagnosed with CCA, smoking, alcohol consumption, and hepatitis B and C. The risk of DM in subjects having FLD was highly significant compared with the non-DM subjects (OR 2.13; 95%CI: 1.92 to 2.35; p-value < 0.001). Thus DM is significantly associated with FLD which in turn may facilitate the development of several diseases including CCA. DM should be taken into consideration in future ultrasonic investigations of FLD and CCA. |
คำสำคัญ |
Fatty liver - diabetes mellitus - ultrasonography - screening - Thailand |
ผู้เขียน |
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การประเมินบทความ |
มีผู้ประเมินอิสระ |
สถานภาพการเผยแพร่ |
ตีพิมพ์แล้ว |
วารสารมีการเผยแพร่ในระดับ |
นานาชาติ |
citation |
มี |
เป็นส่วนหนึ่งของวิทยานิพนธ์ |
เป็น |
แนบไฟล์ |
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Citation |
1
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