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Publication
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| Research Title |
Effect of Direct-Fed Microbials or Probiotics on Intestinal Mucosal Morphology in Broiler Chickens: A Systematic Review and Meta-Analysis |
| Date of Distribution |
30 March 2017 |
| Conference |
| Title of the Conference |
18th Khon Kaen Veterinary Annual International Conference 2017 “Safe food & Good practice for One Health”. |
| Organiser |
Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, Thailand. |
| Conference Place |
AVANI Khon Kaen Hotel & Convention Centre, Khon Kaen, Thailand. |
| Province/State |
Khon Kaen |
| Conference Date |
30 March 2017 |
| To |
31 March 2017 |
| Proceeding Paper |
| Volume |
1 |
| Issue |
1 |
| Page |
64 |
| Editors/edition/publisher |
Kochakorn Direksin, Peerapol Sukon, Kishio Hatai, Nguyen Hoai Nam, A publication of Faculty of Veterinary Medicine, Khon Kaen, Thailand. |
| Abstract |
Title: Effect of Direct-Fed Microbials or Probiotics on Intestinal Mucosal Morphology in Broiler Chickens: A Systematic Review and Meta-Analysis
Authors: Chhaiden Heak1, Peerapol Sukon1,2*, Saijai Kongpechr1, Bundit Tengjaroenkul1, Kanlaya Chuachan1, Nguyen Hoai Nam3
1 Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen University, Khon Kaen 40002, Thailand
2Research Group for Preventive Technology in Livestock, Khon Kaen University, Khon Kaen University, Khon Kaen 40002, Thailand
3Faculty of Veterinary Medicine, Hanoi University of Agriculture, Vietnam
*Corresponding author e-mail: sukonp@kku.ac.th
Abstract
Objective: This systematic review and meta-analysis was conducted to evaluate effect of direct-fed microbials (DFM) or probiotics on intestinal mucosal morphology in broiler chickens.
Materials and Methods: We collected the relevant studies by searching PubMed, SCOPUS, Poultry Science Journal and Google Scholar. We included studies of randomized and non-randomized controlled trials using DFM in broiler chickens and reporting intestinal morphology as an outcome. Overall effect was evaluated using standardized mean difference (SMD) with random effects meta-analysis. In addition, we evaluated for study quality using SYRCLE’s risk of bias tool and for publication bias.
Result: We identified 26 studies (with a total of 55 comparisons) that met our inclusion criteria. Application of DFM in broiler chickens was associated with increasing villus height in the small intestine (SMD=3.91, 95% confident interval (CI) [3.25 to 4.56], p-value <0.001) and with greater villus height to crypt depth ratio in the small intestine (SMD=2.40, 95% CI [1.82 to 2.99, p-value <0.001). However, the quality of the included studies was low or unclear based on the assessment of their risk of bias. Publication bias was also observed.
Conclusion: Application of DFM in broiler chickens was associated with improving intestinal mucosal morphology. However, this evidence is uncertain because of low or unclear quality of included studies and the presence of publication bias.
Keywords: Direct-Fed Microbials, Probiotics, Broiler Chickens, Intestinal Morphology, Systematic Review, Meta-Analysis
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| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
นานาชาติ |
| Type of Proceeding |
Abstract |
| Type of Presentation |
Oral |
| Part of thesis |
true |
| Presentation awarding |
false |
| Attach file |
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| Citation |
0
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Journal Publication
ไทย