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Publication
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| Research Title |
CHRONIC EFFECTS OF THAI BLACK RICE EXTRACT INGESTION ON BLOOD LIPID PROFILES IN THAI SUBJECTS WITH DYSLIPIDEMIA: A PILOT STUDY |
| Date of Distribution |
22 January 2015 |
| Conference |
| Title of the Conference |
International Conference on Research for Social Devotion In Commemoration of the 50th Anniversary of KhonKaen University, Thailand |
| Organiser |
KhonKaen University |
| Conference Place |
KhonKaen University, Thailand |
| Province/State |
KhonKaen University, Thailand |
| Conference Date |
22 January 2015 |
| To |
23 January 2015 |
| Proceeding Paper |
| Volume |
January,22-23,2015 |
| Issue |
January,22-23,2015 |
| Page |
224-225 |
| Editors/edition/publisher |
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| Abstract |
Introduction: Black rice extract is the natural product that contains dietary fiber and antioxidant especially anthocyanin. Anthocyanin has hypocholeslerolemic effect that may improve dyslipidemia which is one of the major risk factors of cardiovascular diseases. However, there is no study investigating the effects of Thai Black rice extract ingestion on blood lipid profiles in Thai subjects with dyslipidemia.
Objectives: To investigate the chronic effects of Thai black rice extract ingestion on fasting blood lipid profiles in Thai subjects with dyslipidemia.
Methods: Ten dyslipidemia subjects (9 women and 1 men, aged 48.93±1.30 years) with dyslipidemia were randomly divided into two groups (n=5/group). They ingested 3 capsules (1 capsule contained 400 mg of black rice extract, 0.86 mg. of anthocyanin) or placebo three times per day for 35 days. After overnight fasting, resting heart rate, blood pressure, blood chemistry (lipid profiles, glucose and hsCRP) and anthropometric parameters (body mass, body height, body mass index and waist and hip circumferences) were measured before and after 35-day ingestion of Thai black rice extract or placebo.
Results: In Thai Black rice extract ingestion group, the total cholesterol (200.8±12.7, 192.2±12.1 mg/dL, p0.01) and glucose (94.2±3.08, 81.0±5.16 mg/dL, p0.01) levels of fasting blood were decreased after the ingestion. However there were no significant differences in all parameters between the groups. Moreover, hsCRP concentration did not change after the ingestion in both groups.
Conclusions: These results suggest that Thai Black rice extract had tendency to improve lipid profiles in Thai subjects with dyslipidemia. Further study investigating the chronic effect of Thai Black rice extract ingestion on lipid profiles and related parameters with a larger number of Thai subjects with dyslipidemia is needed. The unaltered hsCRP concentration may primarily imply that Thai Black rice extract ingestion did not cause general inflammation.
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| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
นานาชาติ |
| Type of Proceeding |
Abstract |
| Type of Presentation |
Poster |
| Part of thesis |
false |
| Presentation awarding |
false |
| Attach file |
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| Citation |
0
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Journal Publication
ไทย