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Publication
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| Title of Article |
Design and functions of a new conical positive expiratory pressure device to be used during exercise: physical characteristic and safety. |
| Date of Acceptance |
7 January 2018 |
| Journal |
| Title of Journal |
Respiratory Care Jounual |
| Standard |
ISI |
| Institute of Journal |
The American Association for Respiratory Care |
| ISBN/ISSN |
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| Volume |
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| Issue |
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| Month |
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| Year of Publication |
2018 |
| Page |
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| Abstract |
Introduction: A flow-dependent conical-PEP (C-PEP) resistor, incorporated into a face mask, was developed which might reduce dyspnea and dynamic hyperinflation and increase exercise endurance for COPD patients. We reported here the flow-pressure relationships and the safety and suitability of the device when used by healthy young and older subjects.
Methods: The flow-pressure relationships were determined for a range of resistors with different orifice diameter and cone length. A 1 cm C-PEP with a 6 or 7 mm orifice was used during a cycle exercise test (60% heart rate reserve, HRR) in 15 young (24.3±3.9 yrs) and 12 older (64.4±3.5 yrs) adults. Cardiopulmonary function and dyspnea were monitored during for up to 10 minute of exercise for up to 10 minute.
Results: For a given flow, pressure decreased as cone length and orifice size increased. A 1 cm C-PEPcone with 6 and 7 mm orifice generated pressures of between 5.24±0.17 and 18.29±0.34 cm H2O at flow rate 0.5 and 0.9 L/sec, and, 4.88±0.13 and 19.14±0.10 cm H2O at flow rate 0.5 and 1.1 L/sec respectively, such as might occur during exercise. The choice of orifice size for a subject depended on their estimated expiratory flow, larger flows required the larger orifice to generate an expiratory pressure of between 5 and 20 cm H2O.
Breathing with C-PEP did not affect exercise time, dyspnea, minute ventilation, heart rate or blood pressure. Pulse oxygen saturation was slightly lower and end tidal CO2 somewhat higher than during control exercise but differences were not significant. There was were no adverse physiological consequences.
Conclusion: A conical-PEP of 1 cm length with orifice of 6 or 7 mm generates an effective expiratory pressure for most subjects during exercise. There were no adverse effects in healthy young and older subjects and the device is suitable for trials with COPD patients.
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| Keyword |
Pressure-flow relationship, PEP device, exercise, cardiopulmonary function, randomized trial, physiotherapy |
| Author |
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| Reviewing Status |
มีผู้ประเมินอิสระ |
| Status |
ได้รับการตอบรับให้ตีพิมพ์ |
| Level of Publication |
นานาชาติ |
| citation |
false |
| Part of thesis |
true |
| Attach file |
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| Citation |
0
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Journal Publication
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