| Research Title |
Inhibition of Nitric Oxide Production by Derrris scandens (Rob.) Benth Extract in UVB-Exposed Human Keratinocytes |
| Date of Distribution |
1 June 2016 |
| Conference |
| Title of the Conference |
CDD 2016 The4th Current Drug Development International Conferrence 2016 |
| Organiser |
Faculty of Pharmaceutical Sciences, Prince of Songkhla University |
| Conference Place |
Phuket Graceland Resort & Spa, Patong Beach |
| Province/State |
Phuket |
| Conference Date |
1 June 2016 |
| To |
3 June 2016 |
| Proceeding Paper |
| Volume |
4 |
| Issue |
1 |
| Page |
146-147 |
| Editors/edition/publisher |
Jaraithip Wungsintaweekul/ Sirinya Keawnoi |
| Abstract |
Ultraviolet B induces skin inflammation and causes sunburn. Derris scandens (Roxb.) Benth (Fabaceae) is a Thai medicinal plant with anti-inflammatory activities. However, there has been no report for the inhibition effect on UVB-induced skin inflammation. The purpose of this study was to investigate the anti-inflammation activity by inhibition of nitric oxide production of D. scandens extract on UVB-exposed human keratinocyte (HaCaT). It was found that exposure of UVB to HaCaT for 30 minutes showed cell shrinkage and produced nitric oxide more than non-UVB exposed cells. D. scandens extract showed anti-inflammatory effect in the treated HaCaT both before and after exposed to UVB. The level of NO after exposed to UVB was slightly lower than that level before UVB exposure indicated that D. scandens extract possessed mildly UVB protection effect to human keratinocyte from UVB-induced inflammation. In addition, from its anti-inflammatory effect, D. scandens has the potential for an ingredient in sunscreen product. |
| Author |
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| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
นานาชาติ |
| Type of Proceeding |
Full paper |
| Type of Presentation |
Oral |
| Part of thesis |
true |
| Presentation awarding |
true |
| Award Title |
Student Traveling Grant |
| Type of award |
รางวัลด้านวิชาการ วิชาชีพ |
| Organiser |
Faculty of Pharmaceutical Sciences, Prince of Songkhla University |
| Date of awarding |
1 มิถุนายน 2559 |
| Attach file |
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| Citation |
0
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Publication
Journal Publication
ไทย