| Research Title |
In Vitro Amoebicidal Activity of Rhinacanthus nasutus Ethanolic Extracts on Acanthamoeba Cysts |
| Date of Distribution |
9 March 2018 |
| Conference |
| Title of the Conference |
The 19th National Graduate Research Conference |
| Organiser |
Graduate School Khon Kaen University |
| Conference Place |
Poj Sarasin Building Khon Kaen University |
| Province/State |
Khon Kaen |
| Conference Date |
9 March 2018 |
| To |
9 March 2018 |
| Proceeding Paper |
| Volume |
19 |
| Issue |
19 |
| Page |
746-754 |
| Editors/edition/publisher |
|
| Abstract |
Amoebae of the genus Acanthamoeba genus are causative agents of amoebic keratitis, granulomatous
amoebic encephalitis and other disseminated diseases. Treatment of acanthamoebiasis is difficult because the cyst
form is less susceptible to amoebicidal agents than the trophozoite stage. The long duration of treatment and lack of a suitable drug to combat Acanthamoeba infections is a hindrance to success. The efficacy and low toxicity of plant
extracts medical usage suggest a promising alternative approach. In this study, ethanolic extracts from Rhinacanthus
nasutus, known as the white crane flower, were used for in vitro cysticidal assays against Acanthamoeba cysts at various concentrations (0.012, 0.12, 1.2, 12 and 120 mg/ml). A concentration of 120 mg/ml killed 100% of
Acanthamoeba cysts after exposure for 24 h, while the other lower concentrations could not completely kill. In
conclusion, ethanolic extractof R.nasutus can be considered anew natural agent against Acanthamoeba cysts. |
| Author |
|
| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
ชาติ |
| Type of Proceeding |
Full paper |
| Type of Presentation |
Poster |
| Part of thesis |
true |
| Presentation awarding |
false |
| Attach file |
|
| Citation |
0
|
|
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Publication
Journal Publication
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