|
|
Publication
|
| Research Title |
Benzoyltyramine Alkaloids Atalantums A-G with Their Cytotoxicity against Cholangiocarcinoma Cell Line from the Peels of Atalantia monophylla |
| Date of Distribution |
3 September 2017 |
| Conference |
| Title of the Conference |
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA Basel 2017) |
| Organiser |
Society for Medicine Plant and Natural Product Research |
| Conference Place |
Basel, Switzerland |
| Province/State |
Basel |
| Conference Date |
3 September 2017 |
| To |
7 September 2017 |
| Proceeding Paper |
| Volume |
4 |
| Issue |
S 01 |
| Page |
DOI : 10.1055/s-00032099 |
| Editors/edition/publisher |
|
| Abstract |
he extraction and isolation of the peels of Atalantia monophylla using chromatographic methods afforded seven new benzoyltyramines, atalantums A-G (1 – 7), along with five known compounds [1]. The structures of these compounds were elucidated based on the analysis of spectroscopic data. Compound 5 displayed the strongest cytotoxicity against KKU-M156 cells, with an IC50 value of 1.97 ± 0.73 µM, an approximately 4.7-fold higher activity than that of the ellipticine standard [2]. Compound 1 was active against KKU-M214 cells, with an IC50 value of 3.06 ± 0.51 µM. For KKU-M213 cell line, compounds 2, 4, and 11 displayed stronger cytotoxicity than the ellipticine standard, with IC50 values of 2.36 ± 0.20, 5.63 ± 0.22, and 2.71 ± 0.23 µM, respectively. Compounds 1, 5, and 7 displayed cytotoxicity against KKU-M214 cells, with IC50 values of 3.06 ± 0.51, 8.44 ± 0.47, and 7.37 ± 1.29 µM, respectively [3]. |
| Author |
|
| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
นานาชาติ |
| Type of Proceeding |
Abstract |
| Type of Presentation |
Poster |
| Part of thesis |
true |
| ใช้สำหรับสำเร็จการศึกษา |
ไม่เป็น |
| Presentation awarding |
false |
| Attach file |
|
| Citation |
0
|
|
|
|
|
|
|
|
|
Journal Publication
ไทย