2012 ©
             Publication
Journal Publication
Title of Article Cervical Cancer in Khon Kaen, Thailand: Analysis of 1990-2014 Incidence Data and Prediction of Future Trends 
Date of Acceptance 27 January 2019 
Journal
     Title of Journal Asian Pacific Journal of Cancer Prevention (APJCP) 
     Standard SCOPUS 
     Institute of Journal Asia Pacific Organization for Cancer Prevention (APOCP) 
     ISBN/ISSN  
     Volume 20 
     Issue
     Month February
     Year of Publication 2019 
     Page 369-375 
     Abstract Background: Cervical cancer is the second most common cancer of women in Thailand. There have been no reports of incidence and future in Khon Kaen, a province in northeastern Thailand, where the relatively high prevalence gives evaluation of cervical cancer screening a high priority. Objectives: To determine cervical cancer incidence rates in Khon Kaen for 1990–2014 and predict future trends until 2029. Methods: Cancer incidence data from the Khon Kaen population-based cancer registry were analyzed and age-standardized incidence rates (ASR) were estimated. Joinpoint analysis and age-period-cohort modeling were applied for data from 1990 to 2014 and the Nordpred package was employed to project trends from 2015 to 2029. Results: Between 1990 and 2014, a total of 3,258 cases were diagnosed with ICD-O code C53 (invasive cervical cancer). Before 2005, an annual percentage change (APC) varied widely, with outliers in 1993 and 1999. The APC computed with the Joinpoint software decreased at -2.8% (95% CI;-4.5 to -1.1) per year on average. After 2005, a rise was noted until 2008, after which a drop became apparent with an APC of -8.0% (95% CI; -14.5 to -1.1) per year on average. Both period and cohort effects played a role in shaping the decrease in incidence. The three projection method suggested that incidence rates would continue to decrease in the future. Conclusions: A decreasing trend in incidence of cervical cancer in Khon Kaen was noted from 1990 to 2014 with a prediction of continuous decrease until 2029. Maintenance and improvement of the screening program is advised. 
     Keyword Cervical cancer; Time trend; Population-based cancer registry data 
Author
587110017-2 Miss THITIMA SAENRUEANG [Main Author]
Public Health Doctoral Degree

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