| Title of Article |
Agreement of tuberculin skin test and Quantiferon®-TB Gold-In-Tube for screening Mycobacterium tuberculosis infection in healthcare workers in a university hospital
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| Date of Acceptance |
30 January 2019 |
| Journal |
| Title of Journal |
Journal of the Medical Association of Thailand |
| Standard |
SCOPUS |
| Institute of Journal |
แพทยสมาคมแห่งประเทศไทย ในพระบรมราชูปถัมภ์ |
| ISBN/ISSN |
0125-2208 |
| Volume |
102 |
| Issue |
Suppl.1 |
| Month |
January |
| Year of Publication |
2019 |
| Page |
S13 - S20 |
| Abstract |
Background: Healthcare workers (HCWs) have a high occupational risk for tuberculosis (TB) infection. Common methods of screening for TB infection are the tuberculin skin test (TST) and interferon-gamma release assays (IGRAs).
Objective: This aim of this study was to investigate the agreement of TST and IGRA (QFT-GIT) as applied to HCWs at a large university hospital in northeast of Thailand.
Material and Methods: The study population included the preplacement medical records of new employees who were tested with both TST and QFT-GIT, comprising 212 HCWs. Eligible for data analysis were 197 participants (calculated sample size was 196). SPSS version19.0 was used to analyse Cohen’s kappa coefficient.
Results: The samples included 197 HCWs: 63 males (32.0%), 134 females (68.0%), 133 physicians (67.5%) and 64 nurses (32.5%). The mean age was 25.6 years (SD = 3.12). Thirty-eight workers (19.3%) tested positive in the TST and 19 workers (9.6%) were QFT-GIT-positive. The total agreement of TST and QFT-GIT was 88.3 (K = 0.54). Forty workers (20.3%) were positive in at least one test.
Conclusions: This study showed moderate agreement of TST and QFT-GIT, which was consistent with the previous studies in high tuberculosis-burden countries (TBC). The authors suggest that pre-placement HCWs in Thailand should be screened for TB infection using the QFT-GIT method.
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| Keyword |
tuberculin skin test, QuantiFERON, IGRA, healthcare workers, tuberculosis |
| Author |
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| Reviewing Status |
มีผู้ประเมินอิสระ |
| Status |
ตีพิมพ์แล้ว |
| Level of Publication |
นานาชาติ |
| citation |
false |
| Part of thesis |
true |
| ใช้สำหรับสำเร็จการศึกษา |
ไม่เป็น |
| Attach file |
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| Citation |
0
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Publication
Journal Publication
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