2012 ©
             Publication
Journal Publication
Title of Article Thai glutinous rice starch modified by ball milling and its application as a mucoadhesive polymer 
Date of Acceptance 29 December 2019 
Journal
     Title of Journal Carbohydrate Polymer 
     Standard SCOPUS 
     Institute of Journal Carbohydrate Polymer 
     ISBN/ISSN 2019 Elsevier Ltd 
     Volume 232 
     Issue 115812 
     Month March
     Year of Publication 2020 
     Page  
     Abstract This study aimed to investigate physicochemical properties and potential application as a mucoadhesive polymer of Thai glutinous rice starch modified by planetary ball milling. XRD and ATR-FTIR results indicated a reduction in crystallinity of starch after ball milling. Different ball milling times, ranging from 5 to 45 min, resulted in modified glutinous rice starch (MGRS) with different levels of crystallinity loss, and therefore varying degrees of cold water solubility, swelling capacity, and gelatinized dispersion viscosity. Investigation of mucoadhesive properties using Texture Analyzer with porcine mucosa demonstrated that MGRS tablets exhibited greater mucoadhesive abilities compared to hydroxypropyl methylcellulose tablets, but weaker than those of sodium carboxymethylcellulose tablets. Tablets made of 15-min-milled MGRS had comparable tableting, swelling and mucoadhesiveness, but lower erosion compared to 45-min-milled MGRS. Conclusively, ball milling treatment could successfully induce the mucoadhesive properties of Thai glutinous rice starch and expand its application as mucoadhesive polymer. 
     Keyword Waxy rice starch, Planetary ball milling, Modified glutinous rice starch, Physical modification, Mucoadhesive polymer, Buccal tablets 
Author
597150006-4 Ms. MAY THU SOE [Main Author]
Pharmaceutical Sciences Doctoral Degree

Reviewing Status มีผู้ประเมินอิสระ 
Status ตีพิมพ์แล้ว 
Level of Publication นานาชาติ 
citation false 
Part of thesis true 
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