|
|
Publication
|
| Title of Article |
Atalantums H-K from the peels of Atalantia monophylla and their cytotoxicity |
| Date of Acceptance |
26 January 2019 |
| Journal |
| Title of Journal |
NATURAL PRODUCT RESEARCH |
| Standard |
ISI |
| Institute of Journal |
Informa UK Limited, trading as Taylor & Francis Group |
| ISBN/ISSN |
|
| Volume |
2019 |
| Issue |
|
| Month |
|
| Year of Publication |
2019 |
| Page |
|
| Abstract |
Four new benzoyltyramines, atalantums H-K (1-4) were isolated from the peels of Atalantia monophylla. All compounds were tested for cytotoxicity against HeLa, HCT116 and MCF-7 cell lines, as well as normal cells (Vero cells). Compound 5 showed cytotoxicity against HeLa, HCT116 and MCF-7 cell lines with IC50 values ranging from 16-25 ug/mL but was inactive against Vero cells. Compound 6 also showed interesting results as compound 5 with IC50 values ranging from 15-18 g/mL and an IC50 value of 80.20 ug/mL against Vero cells. This means compounds 5 and 6 can be used as lead compounds for anticancer agents. |
| Keyword |
Atalantia monophylla, atalantum, benzoyltyramine |
| Author |
|
| Reviewing Status |
มีผู้ประเมินอิสระ |
| Status |
ตีพิมพ์แล้ว |
| Level of Publication |
นานาชาติ |
| citation |
true |
| Part of thesis |
true |
| Attach file |
|
| Citation |
0
|
|
|
|
|
|
|
|
|
Journal Publication
ไทย