2012 ©
             Publication
Journal Publication
Title of Article Gene expression of fatty acid binding protein genes and its relationship with fat deposition of Thai native crossbreed chickens 
Date of Acceptance 3 April 2020 
Journal
     Title of Journal Asian-Australasian Journal of Animal Sciences (AJAS) 
     Standard ISI 
     Institute of Journal An official Journal of Asian-Australasian Association of Animal Production Societies (AAAP) 
     ISBN/ISSN 10112367 
     Volume 2020 
     Issue  
     Month
     Year of Publication 2020 
     Page  
     Abstract Objective The objectives of this study were to investigate the relationship between the mRNA expression of Adipocyte type Fatty Acid Binding Protein (A-FABP) and Heart type FABP (H-FABP) in Thai native chicken crossbreeds and evaluate the level of exotic inclusion in native chicken that will improve growth while maintaining its relatively low carcass fat. Methods The fat deposition traits and mRNA expression of A-FABP and H-FABP were evaluated at 6, 8, 10 and 12 weeks of age in 4 chicken breeds (n=8 /breed/week) [100% Chee breed (CH) (100% Thai native chicken background), CH male and broiler female (Kaimook e-san1; KM1) (50% CH background), broiler male and KM1 female (Kaimook e-san2; KM2) (25% CH background), and broiler (BR)] using abdominal fat and muscular tissues. Results The BR breed was only evaluated at 6 weeks of age. At week 6, the CH breed had a significantly lower A-FABP expression in abdominal fat and intramuscular fat compared with the other breeds. At 8-12 weeks, the KM2 groups showed significant upregulation (P<0.05) of A-FABP in both ABF and IF compared to the CH and KM1 groups. The expression of H-FABP did not follow any consistent pattern in both Abdominal fat (ABF) and Intramuscular fat (IF) across the different ages. Conclusion Some level of crossbreeding CH chickens can be done to improve growth rate while maintaining their low abdominal and intramuscular fat. The expression level of A-FABP correlate with most fat traits. There was no consistency of H-FABP expression across breed. A-FABPs is involved in fat deposition, genetic markers in these genes could be used in marker assisted studies to select against excessive fat accumulation.  
     Keyword Gene Expression; FABPs; Fat Deposition; Correlation; Crossbreed Chicken 
Author
587030012-7 Mr. SUPANON TOONIM [Main Author]
Agriculture Doctoral Degree

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