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Publication
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| Title of Article |
The Effect of Hypokalemia on Early-onset Peritoneal Dialysis-related Peritonitis |
| Date of Acceptance |
10 November 2020 |
| Journal |
| Title of Journal |
Medico-Legal Update |
| Standard |
SCOPUS |
| Institute of Journal |
Institute of Medico-Legal Publications |
| ISBN/ISSN |
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| Volume |
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| Issue |
Vol. No. 20 issue no.4 |
| Month |
October-December 2020 |
| Year of Publication |
2020 |
| Page |
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| Abstract |
Background: Early-onset peritoneal dialysis-related peritonitis (EOP) increased technique failure and mortality among peritoneal dialysis (PD) patients. However, whether hypokalemia is the risk of EOP remains unclear.
Objective: This retrospective cohort study aimed to identify the association between hypokalemia within the first 3 months after PD initiation and EOP.
Methods: A total of 947 PD patients registered at the Kidney Unit in Chaiyaphum regional hospital from January 2011 to December 2018 were recruited and followed up. The first EOP episode within 6 months after the initiation of PD was a primary outcome. Logistic regression was used to identify the association.
Results: Of the total,485 experienced hypokalemia. 90 patients, developed EOP, 61 were from the hypokalemic group (12.6%). Hypokalemia was a significant risk factor of EOP (OR, 2.46; 95% CI, 1.42 to 3.94; P=0.01), as well as decreased serum bicarbonate level (OR, 0.90; 95%CI, 0.82 to 0.99; P=0.026) and decreased hemoglobin level (OR, 0.65; 95% CI, 0.57 to 0.90; P=0.004) and elevated sodium (OR, 1.07;95% CI, 1.00 to 1.15; P=0.046) while controlling other covariates.
Conclusions: Hypokalemia within the first three months after PD initiation was a significant risk factor of EOP.
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| Keyword |
First episode of peritonitis, hypokalemia, EOP |
| Author |
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| Reviewing Status |
มีผู้ประเมินอิสระ |
| Status |
ได้รับการตอบรับให้ตีพิมพ์ |
| Level of Publication |
นานาชาติ |
| citation |
false |
| Part of thesis |
true |
| Attach file |
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| Citation |
0
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Journal Publication
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