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Publication
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Research Title |
Substrate utilization during low-intensity exercise in Thai patients with uncontrolled diabetes mellitus type 2 |
Date of Distribution |
22 January 2015 |
Conference |
Title of the Conference |
Research for social devotion in commemoration of the 50th anniversary of Khon Kaen University, Thailand |
Organiser |
Khon Kaen University |
Conference Place |
KKU |
Province/State |
Khonkaen |
Conference Date |
22 January 2015 |
To |
23 January 2015 |
Proceeding Paper |
Volume |
1 |
Issue |
1 |
Page |
227 |
Editors/edition/publisher |
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Abstract |
Introduction: Patients with type 2 diabetes mellitus (T2DM) had impaired free fatty acid oxidation leading to increased fat storage and insulin resistance. These factors increased cardiovascular risk. It has been reported that healthy sedentary Thai subjects had greatest fat utilization during low-intensity exercise compared with during higher intensity exercise. Therefore, exercise at low intensity may increase fat utilization resulting in reduced cardiovascular risk in patients with uncontrolled T2DM. However, no study explores the substrate utilization in these patients. This study aimed to investigate substrate utilization during low-intensity exercise in Thai patients with uncontrolled T2DM.
Methods: Five uncontrolled patients with T2DM (age and HbA1c were mean±SD 48.8±9.8 yr and 9.4±0.6.%) performed cycling exercise at 25% of peak oxygen consumption for 20 minutes. During last 5 minutes of the exercise, oxygen consumption and carbondioxide production in expired gaswere used to calculate substrate utilization. Immediately before and after the exercise, venous blood samples were taken to determine blood glucose and lipid profiles concentrations.
Results: During low-intensity exercise, CHO was significantly greater than fat oxidation rate (p˂0.05). However, there were no changes in blood glucose and lipid profiles after the exercise.
Conclusion: These preliminary results suggest that during low-intensity exercise, patients with uncontrolled T2DM had greater CHO than fat oxidation rate.
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Author |
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Peer Review Status |
มีผู้ประเมินอิสระ |
Level of Conference |
นานาชาติ |
Type of Proceeding |
Abstract |
Type of Presentation |
Poster |
Part of thesis |
true |
Presentation awarding |
false |
Attach file |
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Citation |
0
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