|
|
Publication
|
| Research Title |
Effects of glycaemic control and low-intensity exercise on substrate utilization in patients with type 2 diabetes |
| Date of Distribution |
11 June 2015 |
| Conference |
| Title of the Conference |
RGJ-Ph.D. Congress XVI |
| Organiser |
Thailand Resaerch Fund |
| Conference Place |
Jomtien Palm beach Hotel and Resort |
| Province/State |
Chonburi, Thailand |
| Conference Date |
11 June 2015 |
| To |
13 June 2015 |
| Proceeding Paper |
| Volume |
16 |
| Issue |
1 |
| Page |
395 |
| Editors/edition/publisher |
|
| Abstract |
Introduction and Objective
It has been reported that patients with type 2 diabetes mellitus (T2DM) showed impaired resting plasma free fatty acid utilization (1). Exercise is wildly used to improve substrate utilization in these patients. However, no study explores the substrate utilization at rest and during exercise in patients with controlled and uncontrolled T2DM. This study aimed to investigate the effect of glycaemic control indicated by haemoglobin A1c (HbA1C) level and low-intensity exercise on substrate utilization in patients with controlled and uncontrolled T2DM.appear outside the margins.
Methods
Four controlled patients with T2DM (HbA1c ≤ 8.5) and four uncontrolled T2DM (HbA1c ˃ 8.5) performed cycling exercise at 25% of peak oxygen consumption for 20 minutes. At rest and during exercise, 5-min expired gas was collected to calculate substrate utilization. Immediately before and after the exercise, venous blood samples were taken to determine blood HbA1c and insulin concentrations.
Results
At rest, fat oxidation rate was significantly greater in the controlled than the uncontrolled group (p≤0.05) without any difference in carbohydrate (CHO) oxidation rate. During the exercise both groups had significantly greater CHO oxidation rate than at rest (p˂0.05), without any change in fat oxidation rate. However, during the exercise, there were no significant differences in fat and CHO oxidation rates between groups.
Conclusion
These preliminary results suggest that during the resting condition, patients with controlled T2DM had higher fat oxidation rate than uncontrolled counterpart. Low-intensity exercise enhanced CHO oxidation rate in both groups.
|
| Author |
|
| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
ชาติ |
| Type of Proceeding |
Abstract |
| Type of Presentation |
Poster |
| Part of thesis |
true |
| Presentation awarding |
false |
| Attach file |
|
| Citation |
0
|
|
|
|
|
|
|
|
|
Journal Publication
ไทย