| Research Title |
Effect of a single bout of low-intensity exercise on substrate utilization and lipid profiles in patients with T2DM
|
| Date of Distribution |
7 December 2016 |
| Conference |
| Title of the Conference |
3rd Pan-Asian Biomedical Science Conference 2016 |
| Organiser |
Malaysia Biomedical Science Society (MyBIOMED) |
| Conference Place |
Premiera Hotel Kuala Lumpur |
| Province/State |
Kuala Lumpur, Malaysia |
| Conference Date |
7 December 2016 |
| To |
8 December 2016 |
| Proceeding Paper |
| Volume |
- |
| Issue |
- |
| Page |
63-64 |
| Editors/edition/publisher |
|
| Abstract |
Patients with type 2 diabetes mellitus (T2DM) have impaired ability to oxidize lipids. This leads to decreased fat utilization and insulin resistance resulting in increased cardiovascular risk. It has been reported that healthy sedentary Thai subjects had greatest fat utilization during low-intensity exercise compared with higher intensity exercise. Therefore, exercise at low intensity may improve fat utilization resulting in reduced cardiovascular risk in patients with poorly controlled T2DM. However, no previous study explored the substrate utilization in these patients. The purpose of this study was to investigate substrate utilization during low-intensity exercise in Thai patients with poorly controlled T2DM. Sixteen patients with poorly controlled T2DM (age and HbA1c were 53.4±7 yr and 10.1±0.9 % (mean±SD)) performed cycling exercise at 33% of peak oxygen consumption for 20 minutes. Expired oxygen and carbon dioxide gases during the final 5 minutes of resting and while exercising were used to calculate substrate utilization. Immediately before and after the exercise, venous blood samples were taken to determine glucose, lipid profiles and insulin concentrations. The results show that a single bout of low-intensity exercise is associated with increases in fat and carbohydrate utilization (p˂0.001, P<0.05). Moreover, there is higher plasma high density lipoprotein concentration than other lipid profiles during low-intensity exercise (P<0.05). However, there were no changes in blood glucose concentration, other lipid profiles and insulin resistance and beta cell function after the exercise. These study suggest that a single bout of low-intensity exercise improves fat and carbohydrate utilization and plasma HDL in patients with poorly controlled T2DM. |
| Author |
|
| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
นานาชาติ |
| Type of Proceeding |
Abstract |
| Type of Presentation |
Poster |
| Part of thesis |
true |
| Presentation awarding |
false |
| Attach file |
|
| Citation |
0
|
|
|
Publication
Journal Publication
ไทย