Research Title |
Protective Effect of Mucuna pruriens (L.) DC. var. pruriens Seed Extract on Sperm Qualities and Protein Expressions in Testis of Adult Rats Induced with Chronic Stress |
Date of Distribution |
25 March 2021 |
Conference |
Title of the Conference |
การประชุมวิชาการเสนอผลงานวิจัยระดับบัณฑิตศึกษาแห่งชาติ ครั้งที่ 22 |
Organiser |
บัณฑิตวิทยาลัย มหาวิทยาลัยขอนแก่น |
Conference Place |
มหาวิทยาลัยขอนแก่น (ออนไลน์) |
Province/State |
ขอนแก่น |
Conference Date |
25 March 2021 |
To |
25 March 2021 |
Proceeding Paper |
Volume |
22 |
Issue |
22 |
Page |
40 |
Editors/edition/publisher |
|
Abstract |
Stress increases the cortisol levels, resulting in decreasing of testosterone levels and sperm qualities. It also alters the protein expressions in testis. This study aimed to investigate the protective effect of Thai Mucuna pruriens (TMP), possessing antioxidant activities, on reproductive damages in male rats induced with chronic stress (CS). Adult male rats were divided into 4 groups (n=8 each group). Rats in control and CS groups received the distilled water (DW) before stress induction (immobilization for 4 hr. and cold forced swimming for 15 min) and the treated animals received the TMP seed extract at doses of 150 and 300 mg/kgBW. After experiment (81 consecutive days), the TMP extracts of both groups could protect the decrease of testicular and epididymis plus vas deferens weights while increase of testosterone level and sperm qualities. Moreover, TMP changed the expressions testicular proteins as compared to CS group. |
Author |
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Peer Review Status |
มีผู้ประเมินอิสระ |
Level of Conference |
ชาติ |
Type of Proceeding |
Abstract |
Type of Presentation |
Oral |
Part of thesis |
true |
Presentation awarding |
false |
Attach file |
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Citation |
0
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