Research Title |
Clitoria ternatea L. Extract Prevents Glomerular Alteration in L-NAME InducedHypertensive Rats |
Date of Distribution |
25 March 2021 |
Conference |
Title of the Conference |
การประชุมวิชาการเสนอผลงานวิจัยระดับบัณฑิตศึกษาแห่งชาติ ครั้งที่ 22 (ออนไลน์) |
Organiser |
บัณฑิตวิทยาลัย มหาวิทยาลัยขอนแก่น |
Conference Place |
ื์มหาวิทยาลัยขอนแก่น รูปแบบออนไลน์ |
Province/State |
ขอนแก่น |
Conference Date |
25 March 2021 |
To |
25 March 2021 |
Proceeding Paper |
Volume |
22 |
Issue |
22 |
Page |
43 |
Editors/edition/publisher |
|
Abstract |
The purpose of this study was to investigate Clitoria ternatea L. (CT) extract could prevent L-NAME induced hypertension and glomerular damage in rats. Male Sprague-Dawley rats were administered with L-NAME (40 mg/kg/day) and concomitant with vehicle or CT extract (300 mg/kg) for five weeks. Systolic blood pressure was measured once a week. At the end of experiment, kidney tissue samples were collected for glomerular volume and Periodic acid-Schiff stained area fraction analysis. CT extract significantly alleviated an increase of systolic blood pressure and glomerular matrix accumulation (p<0.05). Our results indicate that CT extract prevented the development of hypertension and glomerular anatomical changes induced by L-NAME associated with its anti-inflammatory property. |
Author |
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Peer Review Status |
มีผู้ประเมินอิสระ |
Level of Conference |
ชาติ |
Type of Proceeding |
Abstract |
Type of Presentation |
Oral |
Part of thesis |
true |
Presentation awarding |
false |
Attach file |
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Citation |
0
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