| Research Title |
Clitoria ternatea L. Extract Prevents Glomerular Alteration in L-NAME InducedHypertensive Rats |
| Date of Distribution |
25 March 2021 |
| Conference |
| Title of the Conference |
การประชุมวิชาการเสนอผลงานวิจัยระดับบัณฑิตศึกษาแห่งชาติ ครั้งที่ 22 (ออนไลน์) |
| Organiser |
บัณฑิตวิทยาลัย มหาวิทยาลัยขอนแก่น |
| Conference Place |
ื์มหาวิทยาลัยขอนแก่น รูปแบบออนไลน์ |
| Province/State |
ขอนแก่น |
| Conference Date |
25 March 2021 |
| To |
25 March 2021 |
| Proceeding Paper |
| Volume |
22 |
| Issue |
22 |
| Page |
43 |
| Editors/edition/publisher |
|
| Abstract |
The purpose of this study was to investigate Clitoria ternatea L. (CT) extract could prevent L-NAME induced hypertension and glomerular damage in rats. Male Sprague-Dawley rats were administered with L-NAME (40 mg/kg/day) and concomitant with vehicle or CT extract (300 mg/kg) for five weeks. Systolic blood pressure was measured once a week. At the end of experiment, kidney tissue samples were collected for glomerular volume and Periodic acid-Schiff stained area fraction analysis. CT extract significantly alleviated an increase of systolic blood pressure and glomerular matrix accumulation (p<0.05). Our results indicate that CT extract prevented the development of hypertension and glomerular anatomical changes induced by L-NAME associated with its anti-inflammatory property. |
| Author |
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| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
ชาติ |
| Type of Proceeding |
Abstract |
| Type of Presentation |
Oral |
| Part of thesis |
true |
| Presentation awarding |
false |
| Attach file |
|
| Citation |
0
|
|
|
Publication
Journal Publication
ไทย