| Title of Article |
Risk factors for canine magnesium ammonium phosphate urolithiasis associated with bacterial infection |
| Date of Acceptance |
4 November 2021 |
| Journal |
| Title of Journal |
Journal of Veterinary Science |
| Standard |
SCOPUS |
| Institute of Journal |
Korean Society of Veterinary Science |
| ISBN/ISSN |
|
| Volume |
23 |
| Issue |
1 |
| Month |
January |
| Year of Publication |
2022 |
| Page |
|
| Abstract |
Background: With limited information available, the association among urinary tract
infections, urease-producing bacteria and the presence of magnesium ammonium phosphate
(MAP) urolithiasis in canines in Thailand requires more study.
Objectives: This study aimed to investigate the association between demographic
characteristics of canines and the presence of MAP urolithiasis in canines, and to evaluate
antimicrobial susceptibility patterns of bacteria isolated from canine uroliths.
Methods: A total of 56 canines admitted for treatment with surgical removal of uroliths
were recruited. Demographic characteristics and clinical chemistry data were recorded.
Bacteria isolated from the removed uroliths were identified. Chemical compositions of the
uroliths were analyzed by Fourier transform infrared spectrometer. Potential risk factors were
determined with univariable and multivariable logistic regression analyses.
Results: Of 56 canine urolithiasis, bacteria were isolated from uroliths of 38 canines (27 MAP and
11 non-MAP) but not from uroliths of 18 canines (5 MAP and 13 non-MAP). The most common
bacteria found in nidus of MAP uroliths was Staphylococcus pseudintermedius (approximately 51%).
An antimicrobial resistance was frequently found in Staphylococci isolates (42.86%). Multivariate
logistic regression analysis showed that the predictors of MAP urolith in canine urolithiasis were
being female (p = 0.044; adjusted odds ratio [OR], 10.22; 95% confidence interval [CI], 1.06–
98.24) and the positive urolith culture (p = 0.012; adjusted OR, 8.60; 95% CI, 1.60–46.30).
Conclusions: Our results indicate that S. pseudintermedius (a urease-producing bacterium) is
the major causative bacteria of MAP uroliths. A positive urolith culture and being female are
risk factors of MAP urolithiasis in canines. |
| Keyword |
Risk factors; dog; magnesium ammonium phosphate; urolithiasis; bacterial infection |
| Author |
|
| Reviewing Status |
มีผู้ประเมินอิสระ |
| Status |
ตีพิมพ์แล้ว |
| Level of Publication |
นานาชาติ |
| citation |
false |
| Part of thesis |
true |
| Attach file |
|
| Citation |
0
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Publication
Journal Publication
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