2012 ©
             Publication
Journal Publication
Title of Article Evaluation of aqueous and ethanol extracts of Cyperus rotundus L. on sexual behaviours and reproductive fitness in Drosophila melanogaster 
Date of Acceptance 20 March 2021 
Journal
     Title of Journal Pharmaceutical Sciences Asia 
     Standard SCOPUS 
     Institute of Journal Mahidol University – Faculty of Pharmacy 
     ISBN/ISSN ISSN: 25868195, 25868470 
     Volume 48 
     Issue
     Month
     Year of Publication 2021 
     Page 516-522 
     Abstract Cyperus rotundus L. has been used in Ayurvedic and Egyptian folk medicine as an aphrodisiac, no experimental prove has been confirmed for this affirmation. In this study, we aimed to evaluate aqueous and ethanol extract of C. rotundus L. on sexual behaviors and reproductive fitness in Drosophila melanogaster. C. rotundus was extracts in water (WCE) and ethanolic (HECE). Their extracts were supplemented in diets in D. melanogaster. The results revealed that the 5 and 10 mg/mL HECE treatment significantly decreased the duration time of mating latency, significantly prolonged the copulation duration and produced the maximum number of eggs laying of Drosophila, particularly at 10 mg/mL HECE supplemented diet. Moreover, as to fertility, supplementation with 5 and 10 mg/mL HECE in Drosophila significantly increased the number of progenies produced from the mated females. In contrast, 5 and 10 mg/mL WCE treatment didn’t have effect on the duration time of mating latency and the number of progenies in Drosophila compared to the untreated controls. In conclusion, an ethanolic extract of C. rotundus exhibits potential of sexual behaviors and reproductive fitness in Drosophila. Our finding might contribute to the potential pharmacological effect of C. rotundus ethanol extract as aphrodisiac agent 
     Keyword Cyperus rotundus L., Aphrodisiac, Drosophila melanogaster, Reproductive fitness 
Author
617020005-3 Mr. NATTAPONG WONGCHUM [Main Author]
Science Doctoral Degree

Reviewing Status มีผู้ประเมินอิสระ 
Status ตีพิมพ์แล้ว 
Level of Publication นานาชาติ 
citation true 
Part of thesis true 
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