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Publication
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| Title of Article |
Simultaneous preconcentration and fluorescence detection of ATP by a hybrid nanocomposite of magnetic nanoparticles incorporated in mixed metal hydroxide |
| Date of Acceptance |
25 November 2021 |
| Journal |
| Title of Journal |
Analytical Methods |
| Standard |
ISI |
| Institute of Journal |
Royal Society of Chemistry (RSC) |
| ISBN/ISSN |
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| Volume |
2022 |
| Issue |
14 |
| Month |
January |
| Year of Publication |
2022 |
| Page |
188-198 |
| Abstract |
A new approach for increasing the sensitivity of adenosine triphosphate (ATP) detection was demonstrated. The assay was based on the synergetic function of a hybrid nanocomposite (MNPs@MMH) composed of
magnetic nanoparticles (MNPs) incorporated in a mixed metal hydroxide (MMH). MNPs@MMH can be
utilized as an efficient green extractant and peroxidase catalyst. The trace level of ATP in the sample
solution was first extracted by the MNPs@MMH hybrid nanocomposite through the ion exchange
properties of MMH and adsorbed on the surface of the MNPs@MMH. The concentration of ATP was
related to the fluorescence intensity of 2,3-diaminophenazine (DAP) generated from peroxidase-like activity of the MNPs in the presence of H2O2 and o-phenylenediamine (OPD). In the presence of ATP,
the active surface of the MNPs was diminished, and the amount of DAP generated was reduced. Thus,
the concentration of ATP was related to the degree of fluorescence decrease compared to the
fluorescence intensity of the system without ATP. Based on the proposed strategy, a highly sensitive
assay for ATP was achieved. This assay exhibited good selectivity for detection of ATP over derivatives
and other common anions. The proposed assay allowed the detection of ATP in a concentration range
of 2.5–20 mM with a detection limit of 0.41 mM. |
| Keyword |
Fluorescent sensor, chemical sensor, peroxidase-like activity, green extraction, hybrid nanocomposite, preconcentration |
| Author |
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| Reviewing Status |
มีผู้ประเมินอิสระ |
| Status |
ตีพิมพ์แล้ว |
| Level of Publication |
นานาชาติ |
| citation |
false |
| Part of thesis |
true |
| Attach file |
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| Citation |
0
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Journal Publication
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