| Abstract |
Introduction. Cardiovascular disease (CVD) is the leading cause of death in Thailand. Dyslipidemia have been known to be high risk for CVD. This may be determined by an impaired aerobic capacity and central obesity which are associated with CVD. However no study investigated this event in dyslipidemia.
Purpose. To investigate relationships between aerobic capacity and serum lipid profiles and central obesity in dyslipidemia
Methods. One-hundred and twenty-four dyslipidemia aged 47.9 ± 0.7 years and 128 healthy sedentary subjects aged 44.7 ± 0.7 years in urban, Khon Kaen province, Thailand were recruited. Blood sample was obtained after a 12-hour fast and analyzed for lipid profiles. Anthropometric and body composition parameters were also investigated. Each subject underwent exercise test for determination of aerobic capacity.
Results. Body mass index, waist circumference, and waist to hip circumference ratio were significantly higher in dyslipidemia than those in healthy sedentary subjects. Aerobic capacity was significantly lower in dyslipidemia (21.5 ± 0.7 ml/kg/min, p < 0.01) than that in the healthy subjects (24.4 ± 0.7 ml/kg/min). Based on Pearson's correlation analysis, aerobic capacity was inversely related to serum low density lipoprotein cholesterol (LDL-C) concentration (r = -0.16, p < 0.05) and positively related to serum high density lipoprotein cholesterol (HDL-C) concentration in dyslpidemia (r = 0.36, p < 0.01). However, aerobic capacity was not related to waist circumference.
Conclusion. This study demonstrates that aerobic capacity and central obesity are independent cardiovascular risk factors in dyslipidemia. |
Publication
Journal Publication
ไทย