| Research Title |
Aortic-femoral pulse wave velocity may be used as a predictor of coronary artery disease severity in the metabolic syndrome patients |
| Date of Distribution |
2 May 2011 |
| Conference |
| Title of the Conference |
The Physiology Society of Thailand |
| Organiser |
Department of Physiology, Faculty of Medicine, Khon Kaen University |
| Conference Place |
Pullman Raja Orchid Khonkaen Hotel |
| Province/State |
Khon Kaen |
| Conference Date |
2 May 2011 |
| To |
4 May 2011 |
| Proceeding Paper |
| Volume |
24 |
| Issue |
1 |
| Page |
120 |
| Editors/edition/publisher |
|
| Abstract |
Metabolic syndrome (MetS) is characterized by multiple risk factors and is associated with increased risk of coronary artery disease (CAD). Recently, arterial stiffness and CAD have been shown to be closely related, but data on the correlation between the severity of CAD and arterial stiffness, especially in MetS patients is very limited. Pulse wave velocity (PWV) is widely recognized as a good marker of arterial stiffness and is now known to be a good prognostic indicator for cardiovascular disease. The aim of this study is to evaluate whether an increase in PWV is associated with the severity of CAD in Thai MetS patients. One hundred and fifty-three patients with mean age of 61.5 ± 0.6 years were enrolled in this study. Routine anthropometric and serologic data were collected. PWV was measured the day before coronary angiography, and the severity of CAD was assessed using the modified Gensini scoring system after angiography. One hundred and eleven patients were classified as MetS according to the National Cholesterol Educational Program-Adult Treatment Panel III (NCEP-ATPIII) and International Diabetes Federation (IDF) criteria. Seventy-three patients with MetS were diagnosed CAD after angiography. Aortic-ankle PWV (aaPWV) and aortic-femoral PWV (afPWV) were significantly increased in MetS patients. The modified Gensini score was significantly correlated to afPWV (r=0.235, p=0.016) after adjustment for factors know to influence PWV, including age, sex, systolic pressure, ankle-brachial pressure index, fasting blood sugar, and high density lipoprotein-cholesterol. Our findings suggest that afPWV, as an established measure of central artery stiffness, may be used as a screening tool for predicting the severity of CAD, especially in patients with metabolic syndrome. |
| Author |
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| Peer Review Status |
ไม่มีผู้ประเมินอิสระ |
| Level of Conference |
นานาชาติ |
| Type of Proceeding |
Abstract |
| Type of Presentation |
Poster |
| Part of thesis |
true |
| ใช้สำหรับสำเร็จการศึกษา |
ไม่เป็น |
| Presentation awarding |
true |
| Award Title |
Award of Excellence 2011 for an outstanding poster presentation at the 40th Annual Scientific Meeting & International Conference of the Physiological Society of Thailand |
| Type of award |
รางวัลด้านวิชาการ วิชาชีพ |
| Organiser |
The Physiological Society of Thailand |
| Date of awarding |
4 พฤษภาคม 2554 |
| Attach file |
|
| Citation |
0
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Publication
Journal Publication
ไทย