|
|
ข้อมูลการเผยแพร่ผลงาน
|
| ชื่อบทความ |
Factors associated with latent tuberculosis infection among the
hospital employees in a tertiary hospital of northeastern Thailand |
| วัน/เดือน/ปี ที่ได้ตอบรับ |
15 กันยายน 2563 |
| วารสาร |
| ชื่อวารสาร |
International Journal of Environmental Research and Public Health |
| มาตรฐานของวารสาร |
TCI |
| หน่วยงานเจ้าของวารสาร |
MDPI IJERPH Editorial Office St. Alban-Anlage 66, 4052 Basel, Switzerland |
| ISBN/ISSN |
Proceedings of ICOH Occupational Health for Health Worker (OHHW2019) Conference |
| ปีที่ |
2020 |
| ฉบับที่ |
17 |
| เดือน |
October |
| ปี พ.ศ. ที่พิมพ์ |
2563 |
| หน้า |
|
| บทคัดย่อ |
Factors associated with latent tuberculosis infection among the hospital employees in a tertiary hospital of northeastern Thailand
Patimaporn Chanpho1,3, Naesinee Chaiear 2,3,* and Supot Kamsa-ard1
1 Department of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University, Khon Kaen 40002; Thailand. patich@kku,ac.th, supot@kku.ac.th
2 Division of Occupational Medicine, Department of Community Medicine, Faculty of Medicine,
Khon Kaen University, Khon Kaen 40002; Thailand naesinee@kku.ac.th
3. Occupational Health and Safety Office, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002; Thailand
patich@kku,ac.th, naesinee@kku.ac.th
* Correspondence: naesinee@kku.ac.th; Tel.:+66-4336-3588
Received: date; Accepted: date; Published: date
Abstract: Latent tuberculosis infection (LTBI) can develop into tuberculosis (TB). The WHO requires the discovery and management of LTBI among high-risk groups. Health care workers (HCWs) constitute a high-risk group. Factors associated with LTBI among HCWs in Thailand needs further study. The current study aimed to explore the factors related to LTBI among Thai HCWs. A hospital-based, matched, case–control study was conducted. All cases and controls were HCWs at a tertiary hospital in northeastern Thailand. Between 2017 and 2019, a total of 85 cases of interferon-γ release assays (IGRAs)-proven LTBI, and 170 control subjects were selected from a hospital (two controls per case). The two recruited controls were individually matched with LTBI cases by sex and age (±5 years). Secondary data were obtained from the occupational health and safety office. Case HCWs had a higher proportion of significant factors than control HCWs (i.e., working closely with pulmonary TB – 94.1% vs. 88.8%, and working in the area of aerosol-generating procedures 81.2% vs. 69.4%). The bivariate conditional logistic regression showed that the occurrence of LTBI in HCWs was statistically significant (p-value < 0.05), particularly with respect to: workplaces with aerosol-generating procedures (AGPs) (crude OR = 1.90, 95% CI: 1.01-3.58, p= 0.041); among HCWs performing AGP (crude OR = 2.04, 95% CI: 1.20, 3.48, p = 0.007; and, absent Bacille Calmette-Guérin (BCG) scar (crude OR = 2.59, 95% CI: 1.50-4.47, p = 0.001). Based on the multivariable conditional logistics analysis, HCWs who performed AGPs while contacting TB cases had a statistically significant association with LTBI (adj OR= 1.82, 95% CI: 1.04-3.20, p=0.035). HCWs who reported the absence of a BCG scar had a statistically significant association with LTBI (adj OR= 2.49, 95% CI: 1.65-5.36, p = 0.001) whereas other factors including close contact with TB (adj OR= 2.44, 95% CI: 0.74, 8.09, p=0123) were not significantly associated with LTBI.
Conclusion: HCWs who performed AGP and were absent a BCG scar had a significant association with LTBI, while other factors played a less critical role.
|
| คำสำคัญ |
latent tuberculosis infection; tuberculosis; health care worker; hospital employee |
| ผู้เขียน |
|
| การประเมินบทความ |
มีผู้ประเมินอิสระ |
| สถานภาพการเผยแพร่ |
ได้รับการตอบรับให้ตีพิมพ์ |
| วารสารมีการเผยแพร่ในระดับ |
นานาชาติ |
| citation |
ไม่มี |
| เป็นส่วนหนึ่งของวิทยานิพนธ์ |
เป็น |
| แนบไฟล์ |
|
| Citation |
0
|
|
|
|
|
|
|
|
|
การเผยแพร่ในรูปของบทความวารสารทางวิชาการ
English