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Publication
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| Title of Article |
Induction of External Infection-models in Experimental Animals: A review |
| Date of Acceptance |
18 May 2015 |
| Journal |
| Title of Journal |
Journal of Science and technology mahasarakham university |
| Standard |
TCI |
| Institute of Journal |
มหาวิทยาลัยมหาสารคาม |
| ISBN/ISSN |
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| Volume |
34 |
| Issue |
5 |
| Month |
กันยายน-ตุลาคม |
| Year of Publication |
2015 |
| Page |
536-546 |
| Abstract |
Infection remains a leading cause of mortality and economic loss. Development of a new effective antimicrobial agent
to combat infection is necessary. In vitro testing is investigated for basic potential, but it is insuffi cient to assure
effi ciency and effi cacy of an antimicrobial agent. Hence, in vivo testing has been recognized as the essential study to
provide reliable information and to support the in vitro data. This review aims to summarize models for the induction
of external infections in experimental animals and categorize by the principles and equipment of the wound inductions,
appearance of the wounds, and strains and species of animals, and microorganisms employed. The induction of
external infection models in animals is divided into 5 categories including skin abrasion infection model, burn wound
infection model, foreign body infection model, lacerated wound infection model and excisional wound infection model.
Thus, the optimal wound induction model depends on the aim(s) of a study and consideration criteria of a
researcher to gain the informative and applicable data |
| Keyword |
external infection, animal model, in vivo, wound |
| Author |
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| Reviewing Status |
มีผู้ประเมินอิสระ |
| Status |
ตีพิมพ์แล้ว |
| Level of Publication |
ชาติ |
| citation |
true |
| Part of thesis |
true |
| Attach file |
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| Citation |
0
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Journal Publication
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