2012 ©
             TH, publication_detail
TH, publication_article
TH, publication_conference_work_name Antifertility effects of Leucaena leucocephala aqueous shoot tips plus young leaves extract in adult male rats 
TH, publication_conference_publish_date 26 January 2017 
TH, publication_conference_conference
     TH, publication_conference_conference_name The 2nd International Conference on Herbal and Traditional Medicine (HTM2017)  
     TH, publication_conference_conference_institute Faculty of Pharmaceutical Sciences, Khon Kaen University 
     TH, publication_conference_conference_place Asia Hotel 
     TH, publication_conference_conference_province Bangkok 
     TH, publication_conference_conference_from_date 25 January 2017 
     TH, publication_conference_conference_to_date 27 January 2017 
TH, publication_conference_proceeding
     TH, publication_conference_proceeding_volume_short
     TH, publication_conference_proceeding_issue_short
     TH, publication_conference_proceeding_page_short 198 
     TH, publication_conference_proceeding_editor_short  
     TH, publication_conference_abstract Introduction: Recently, the antifertility studies of plant or herb are conducting to search for male contraceptive plants that can reduce the side effects from synthetic contraceptives. Although Leucaena leucocephala (LL) can cause hair loss and infertility in cattle, the antifertility effects of LL have never been systemically reported. Therefore, this study aimed to investigate effects of LL aqueous shoot tips plus young leaves extract on reproductive system in male rats. Methods: Shoot tips plus young leaves of LL were harvested in Khon Kaen province. Ten male rats were divided into two groups; control group was orally received with distilled water and LL group was received with 1500 mg/kg BW of LL extract for consecutive 60 days. Results and Discussion: The results showed that LL-treated rats had significant increases of malondialdehyde level, percentage of sperm acrosome reaction, and abnormal sperm head as compared with the control. Additionally, LL extract significantly reduced the sperm count, follicle-stimulating and testosterone hormone levels, and expression of testicular steroidogenic acute regulatory (StAR) protein. Moreover, seminiferous tubular atrophy and few germ cells in some tubules were observed in LL-treated rats. However, the extract had no adverse effect on body and reproductive organ weights, luteinizing hormone level, and expression of tyrosine phosphorylated proteins. Conclusion: These findings suggested that aqueous shoot tips plus young leaves extract of LL has male antifertility property in rats. 
TH, publication_article_writer
577070005-9 Mr. JATURON BURAWAT [TH, publication_article_main_writer]
Medicine Doctoral Degree
577070021-1 Miss SUPATCHAREE ARUN
Medicine Doctoral Degree
567070006-6 Miss WANNISA SUKHORUM
Medicine Doctoral Degree
587070006-8 Mr. APICHAKAN SAMPANNANG
Medicine Doctoral Degree

TH, publication_conference_evaluation มีผู้ประเมินอิสระ 
TH, publication_conference_level นานาชาติ 
TH, publication_conference_proceeding_style Abstract 
TH, publication_conference_presentation_style Oral 
TH, publication_conference_part_of_thesis TH, publication_conference_part_of_thesis_true 
TH, publication_conference_part_of_graduate TH, publication_conference_part_of_graduate_false 
TH, publication_conference_is_reward TH, publication_conference_is_reward_true 
     TH, publication_conference_reward_name Bronze Medal Award (oral presentation) 
     TH, publication_conference_reward_type รางวัลด้านวิชาการ วิชาชีพ 
     TH, publication_conference_reward_institute Faculty of Pharmaceutical Sciences, Khon Kaen University 
     TH, publication_conference_reward_date 27 มกราคม 2560 
TH, publication_attachment_file
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