2012 ©
             Publication
Journal Publication
Title of Article Comparison of three equations for estimating low-density lipoprotein-cholesterol in the rural northeastern region of Thailand 
Date of Acceptance 21 May 2020 
Journal
     Title of Journal Journal of Clinical Laboratory Analysis 
     Standard SCOPUS 
     Institute of Journal wiley only library 
     ISBN/ISSN 0887-8013 
     Volume  
     Issue  
     Month
     Year of Publication 2020 
     Page  
     Abstract Background: Cardiovascular disease is the most common cause of death worldwide, and the detection of LDL-C contributes to reducing risks. However, the LDL-C is rarely evaluated according to the gold standard method because it is costly and time-consuming. This study aimed to determine the agreement of LDL-C among three equations, namely Friedewald's equation, Puavilai's equation, and Dansethakul's equation. Methods: A cross-sectional descriptive study. Results: Using the data of lipid measurement from a specific group of people in the remote rural area, we found that the Thai equations have more superior agreement with direct measurement than the Friedewald equation (ICC = 0.870, 95% CI = 0.857-0.882) when the agreement of continuous data was used for total analysis. Although the categorical analysis that gave better agreement was from Friedewald equation (K index = 0.730, 95% CI = 0.720-0.751), the findings from this study confirmed the population-specific use of Pauvilai's equation and Dansethakul's equation for determining the LDL-C. Conclusion: Pauvilai's equation showed better agreement with direct measurement for LDL-C. Thus, it could be considered as an alternative for the direct method, particularly in laboratories in rural areas in Thailand. 
     Keyword agreement, cardiovascular disease, LDL-C equation, northeastern Thailand, rural area 
Author
605110012-0 Mr. SIRAWICH SONSOK [Main Author]
Public Health Master's Degree

Reviewing Status มีผู้ประเมินอิสระ 
Status ได้รับการตอบรับให้ตีพิมพ์ 
Level of Publication นานาชาติ 
citation true 
Part of thesis true 
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