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Publication
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Title of Article |
Comparison of three equations for estimating low-density
lipoprotein-cholesterol in the rural northeastern region of
Thailand |
Date of Acceptance |
21 May 2020 |
Journal |
Title of Journal |
Journal of Clinical Laboratory Analysis |
Standard |
SCOPUS |
Institute of Journal |
wiley only library |
ISBN/ISSN |
0887-8013 |
Volume |
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Issue |
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Month |
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Year of Publication |
2020 |
Page |
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Abstract |
Background: Cardiovascular disease is the most common cause of death worldwide,
and the detection of LDL-C contributes to reducing risks. However, the LDL-C is rarely
evaluated according to the gold standard method because it is costly and time-consuming. This study aimed to determine the agreement of LDL-C among three equations, namely Friedewald's equation, Puavilai's equation, and Dansethakul's equation.
Methods: A cross-sectional descriptive study.
Results: Using the data of lipid measurement from a specific group of people in the
remote rural area, we found that the Thai equations have more superior agreement
with direct measurement than the Friedewald equation (ICC = 0.870, 95% CI = 0.857-0.882) when the agreement of continuous data was used for total analysis. Although
the categorical analysis that gave better agreement was from Friedewald equation
(K index = 0.730, 95% CI = 0.720-0.751), the findings from this study confirmed the
population-specific use of Pauvilai's equation and Dansethakul's equation for determining the LDL-C.
Conclusion: Pauvilai's equation showed better agreement with direct measurement
for LDL-C. Thus, it could be considered as an alternative for the direct method, particularly in laboratories in rural areas in Thailand. |
Keyword |
agreement, cardiovascular disease, LDL-C equation, northeastern Thailand, rural area |
Author |
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Reviewing Status |
มีผู้ประเมินอิสระ |
Status |
ได้รับการตอบรับให้ตีพิมพ์ |
Level of Publication |
นานาชาติ |
citation |
true |
Part of thesis |
true |
Attach file |
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Citation |
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