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Publication
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Title of Article |
Meroditerpene pyrone, tryptoquivaline and brasiliamide derivatives from
the fungus Neosartorya pseudofischeri |
Date of Acceptance |
1 July 2019 |
Journal |
Title of Journal |
Fitoterapia |
Standard |
ISI |
Institute of Journal |
Elsevier |
ISBN/ISSN |
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Volume |
137 |
Issue |
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Month |
September |
Year of Publication |
2019 |
Page |
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Abstract |
Two new meroditerpene pyrones, chevalone F (1) and 11-hydroxychevalone E (2), a new tryptoquivaline analog,
tryptoquivaline V (3) and a new brasiliamide analog, brasiliamide G (4), together with thirteen known compounds,
chevalones A-C (5–7), chevalone E (8), 11-hydroxychevalone C (9), pyripyropene A (10), isochaetominine
C (11), pyrrolobenzoxazine terpenoids CJ-12662 (12) and CJ-12663 (13), fischerindoline (14),
eurochevalierine (15), 1,4-diacetyl-2,5-dibenzylpiperazine-3,7′′-oxide (16) and lecanorin (17) were isolated
from the fungus Neosartorya pseudofischeri. Their structures were established on the basis of spectroscopic evidence.
Compound 2 showed weak antibacterial activity against Escherichia coli and Salmonella enterica serovar
Typhimurium, whereas compounds 7, 12, 13 and 15 showed antibacterial activity against Bacillus cereus and
Staphylococcus aureus. In addition, compounds 13 and 14 showed cytotoxicity against KB and MCF-7 cancer cell
lines, as well as the Vero cell line. |
Keyword |
Neosartorya pseudofischeri Meroterpenoid Meroditerpene pyrone Tryptoquivaline Brasiliamide Antibacterial Cytotoxicity |
Author |
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Reviewing Status |
มีผู้ประเมินอิสระ |
Status |
ตีพิมพ์แล้ว |
Level of Publication |
นานาชาติ |
citation |
true |
Part of thesis |
true |
Attach file |
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Citation |
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