| Title of Article |
Severity and Management of Adverse Drug Reactions Reported by Patients and Healthcare Professionals: A Cross-Sectional Survey |
| Date of Acceptance |
15 February 2023 |
| Journal |
| Title of Journal |
International Journal of Environmental Research and Public Health |
| Standard |
ISI |
| Institute of Journal |
Multidisciplinary Digital Publishing Institute (MDPI) |
| ISBN/ISSN |
|
| Volume |
20 |
| Issue |
4 |
| Month |
February |
| Year of Publication |
2023 |
| Page |
3725 |
| Abstract |
Adverse drug reaction (ADR) severity levels are mainly rated by healthcare professionals (HCPs), but patient ratings are limited. This study aimed to compare patient-rated and pharmacistrated ADR severity levels and determined methods employed for ADR management and prevention by patients and HCPs. A cross-sectional survey was conducted in outpatients visiting two hospitals. Patients were asked about ADR experiences using a self-administered questionnaire, and additional
information was retrieved from the medical records. In total, 617 out of 5594 patients had experienced
ADRs (11.0%), but 419 patients were valid (68.0%). Patients commonly reported that their ADR
severity level was moderate (39.4%), whereas pharmacists rated the ADRs as mild (52.5%). There
was little agreement between patient-rated and pharmacist-rated ADR severity levels (kappa = 0.144;
p < 0.001). The major method of ADR management by physicians was drug withdrawal (84.7%), while for patients, it was physician consultation (67.5%). The main methods for ADR prevention by patients and HCPs were carrying an allergy card (37.2%) and recording drug allergy history (51.1%), respectively. A higher level of ADR bothersomeness was associated with higher ADR severity levels (p < 0.001). Patients and HCPs rated ADR severity and used ADR management and prevention
methods differently. However, patient rating of ADR severity is a potential signal for severe ADR detection of HCPs. |
| Keyword |
patient self-reporting; adverse drug reactions; severity; management; prevention |
| Author |
|
| Reviewing Status |
มีผู้ประเมินอิสระ |
| Status |
ได้รับการตอบรับให้ตีพิมพ์ |
| Level of Publication |
นานาชาติ |
| citation |
true |
| Part of thesis |
true |
| ใช้สำหรับสำเร็จการศึกษา |
ไม่เป็น |
| Attach file |
|
| Citation |
0
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Publication
Journal Publication
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