Research Title |
cytotoxic and antiestrogenic effect of Momordica cochinchinensis extract on MCF-7 breast cancer cells |
Date of Distribution |
17 September 2012 |
Conference |
Title of the Conference |
The 5th Sino-Thai international conference 2012 |
Organiser |
Guangxi univerasity and KKU |
Conference Place |
Guangxi univerasity |
Province/State |
Nanning, CHINA |
Conference Date |
17 September 2012 |
To |
20 September 2012 |
Proceeding Paper |
Volume |
5 |
Issue |
- |
Page |
444 |
Editors/edition/publisher |
|
Abstract |
Momordica cochinchinensis (MC) Spreng fruit contains high lycopene content. This study aimed to determine the cytotoxic and antiestrogenic effects of aril extract of MC fruit on MCF-7 breast cancer cells. The aril extract showed cytotoxic effect on MCF-7 cells with IC50 at 277.48±14.17 µg/ml. Its cytotoxic effect increased when co-treatment with tamoxifen. The aril extract demonstrated antiestrogenic activity by inhibiting the proliferation of MCF-7 cells induced by 17β-estradiol in a dose dependent manner. |
Author |
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Peer Review Status |
มีผู้ประเมินอิสระ |
Level of Conference |
นานาชาติ |
Type of Proceeding |
Full paper |
Type of Presentation |
Poster |
Part of thesis |
true |
Presentation awarding |
false |
Attach file |
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Citation |
0
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