ชื่อบทความ |
Lack of Association between Red Meat Consumption and a Positive Fecal Immunochemical Colorectal Cancer Screening Test in Khon Kaen, Thailand: a Population- Based Randomized Controlled Trial |
วัน/เดือน/ปี ที่ได้ตอบรับ |
16 ธันวาคม 2560 |
วารสาร |
ชื่อวารสาร |
Asian Pacific Journal of Cancer Prevention |
มาตรฐานของวารสาร |
SCOPUS |
หน่วยงานเจ้าของวารสาร |
Asian Pacific Organization for Cancer Prevention |
ISBN/ISSN |
1513-7368 |
ปีที่ |
19 |
ฉบับที่ |
1 |
เดือน |
January |
ปี พ.ศ. ที่พิมพ์ |
2561 |
หน้า |
271-278 |
บทคัดย่อ |
Background: There is convincing evidence from epidemiological studies that meat consumption increases colorectal cancer (CRC) risk. However, assessment of any association with a positive fecal immunochemical test (FIT) in CRC screening has been limited. If a link could be shown this might be helpful for establishing a risk group for colonoscopy. Objective: This study aimed to assess any association between meat consumption and other lifestyle factors and a positive FIT result in a Thai population. Methods: A cross-sectional analytical study was conducted with 1,167 participants in a population-based randomized controlled trial. CRC was screened from May 2016 - February 2017. Subjects aged 45-74 years who met the eligibility criteria were randomly allocated to the study arm. A positive FIT was determined with cut-off 100 ng/mL. Multiple logistic regression was used to analyze any relationship between lifestyle factors and a positive FIT. Result: The total number of subjects was 1,060 (90.8% return rate of FIT). With FIT100, FIT150, and FIT200, positive tests were found in 92 (8.68%), 74 (6.98%), and 60 (5.66%), respectively. No significant associations were noted with any of the variables, except for being aged 60-74 years (ORadj = 1.62, 95% CI: 1.03-2.54) Borderline significance was observed for high consumption of vegetables (ORadj = 0.62, 95% CI: 0.36-1.07) and being male (ORadj = 1.39, 95% CI: 0.87-2.22). Conclusion: Despite the evidence from the literature, no association was here found between a positive FIT result and meat consumption or other well-established lifestyle parameters. Being aged 60-74 years was a risk factor which should be taken into account in CRC screening strategy in countries like Thailand with limited access to endoscopy. |
คำสำคัญ |
Red meat consumption; fecal immunochemical test; colorectal cancer |
ผู้เขียน |
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การประเมินบทความ |
มีผู้ประเมินอิสระ |
สถานภาพการเผยแพร่ |
ตีพิมพ์แล้ว |
วารสารมีการเผยแพร่ในระดับ |
นานาชาติ |
citation |
มี |
เป็นส่วนหนึ่งของวิทยานิพนธ์ |
เป็น |
แนบไฟล์ |
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Citation |
0
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