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Publication
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| Research Title |
Effect of a new conical-PEP device on cardiopulmonary function
during exercise in elderly |
| Date of Distribution |
5 September 2016 |
| Conference |
| Title of the Conference |
European Respiratory Society International Congress 2016 |
| Organiser |
The European Respiratory Society |
| Conference Place |
The ExCel, London, UK |
| Province/State |
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| Conference Date |
3 September 2016 |
| To |
7 September 2016 |
| Proceeding Paper |
| Volume |
48 |
| Issue |
European Respiratory Journal 2016 48: OA2015; DOI: 10.1183/13993003.congress-2016.OA2015 |
| Page |
OA2015 |
| Editors/edition/publisher |
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| Abstract |
Background: Premature airway closure during exercise is common in elderly leading to dyspnea and exercise intolerance [1]. Positive expiratory pressure (PEP) can reduce airway closure and dyspnea but may lead to CO2 retention affecting cardiovascular function. We investigated the effects and safety of a new conical-PEP (CPEP) device on cardiopulmonary function during exercise in elderly.
Methods: Twelve participants (60-72 yrs, 3 male) performed 2 constant workload cycling tests (53±21W) to symptom limit using either Sham (4.1±2.5 cm H2O) or CPEP (10.4±5.5 cm H2O) breathing in a randomized crossover trial. Slow vital capacity (SVC) and Blood pressure (BP) were assessed at rest and end exercise. End-tidal CO2 (PETCO2), pulse oxygen saturation (SpO2), and heart rate (HR) were monitored every minute, while dyspnea was assessed every 2 minutes during exercise.
Results: Participants stopped exercise after similar times, dyspnea rating and %HRmax (75±14 and 74±14) in both conditions. There was a reduction in SVC with Sham (ΔSVC= -0.36 L, p= 0.037) but not with CPEP (ΔSVC= -0.09 L, p= 0.186). Systolic-BP was lower with CPEP than Sham (mean difference -13.0 mm Hg, p= 0.015). PETCO2 at end exercise was marginally, but not significantly, higher with CPEP. SpO2 did not differ between conditions.
Conclusion: CPEP breathing maintained SVC during exercise but did not improve dyspnea, probably because these fit elderly were not limited by their respiratory function. The absence of CO2 retention and adverse effects indicates that CPEP device may be trialed in patients with reduced lung function. The reduced Systolic-BP response with CPEP may be beneficial in preventing extreme BP responses during exercise. |
| Author |
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| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
นานาชาติ |
| Type of Proceeding |
Abstract |
| Type of Presentation |
Oral |
| Part of thesis |
true |
| Presentation awarding |
false |
| Attach file |
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| Citation |
0
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Journal Publication
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