2012 ©
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Journal Publication
Title of Article COMPARISON OF HEART RATE VARIABILITY BETWEEN PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND NORMAL SUBJECTS 
Date of Acceptance 21 June 2018 
Journal
     Title of Journal International Journal of GEOMATE 
     Standard SCOPUS 
     Institute of Journal Mie University, Japan 
     ISBN/ISSN 2186-2990 
     Volume 2018 
     Issue 49 
     Month October
     Year of Publication 2018 
     Page 124-129 
     Abstract ABSTRACT: Major Depressive Disorder is one of the major mental health problems that affect the quality of life of the patients. The reduced heart rate variability (HRV) and elevated heart rate that associated with depression have been found as risk factors for cardiac mobility and mortality. These patients should be assessed regularly on HRV parameters and compare with those of normal subjects. This study aimed to compare heart rate variability between patients with the major depressive disorder and normal subjects. This study was conducted at a psychiatric department in Khon Kaen University, Srinagarind Hospital, Khon Kaen province, Thailand. A cross-sectional analytic study design was used. Forty patients diagnosed with the major depressive disorder (who had been treated with antidepressants) were matched according to age, gender with 40 normal subjects participated. They were assessed on HRV for time domain (standard deviation normal to normal: SDNN, and the root mean square of successive differences: RMSSD) and frequency domain (High frequency: HF, low frequency: LF, and LF/HF ratio) using SA 3000P Digital. The results showed that The HRV in the patients and in the normal subjects were found with SDNN 28.60, 31.44; RMSSD 23.78, 26.73; HF 4.70, 5.04; LF 4.46, 5.01; and LF/HF 1.16, 1.35 respectively. However, No significant difference in the HRV variables between MDD and normal subjects except LF. Findings of this study show that HRV in the treated patients with major depressive disorder seems to be a little lower than the normal subjects. This may be due to the effects of well treated with antidepressants. It is suggested that HRV may be one of the outcome measures for this patient population. 
     Keyword Major depressive disorder, Heart rate variability, Time domain, Frequency domain 
Author
577090006-5 Mrs. WARANGKANA CHOMPOOPAN [Main Author]
Associated Medical Sciences Doctoral Degree

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Level of Publication นานาชาติ 
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