ชื่อบทความที่เผยแพร่ |
A Study of Bone Invasion in Panoramic Radiography and Cervical Lymph Node Metastasis in Oral Squamous cell carcinoma |
วัน/เดือน/ปี ที่เผยแพร่ |
9 กรกฎาคม 2562 |
การประชุม |
ชื่อการประชุม |
DFCT 2019 THE 17th International Sciencetific Conference of the Dental Faculty Consortium of Thailand |
หน่วยงาน/องค์กรที่จัดประชุม |
มหาวิทยาลัยขอนแก่น |
สถานที่จัดประชุม |
Pullman Raja Orchid Hotel, Khon Kaen |
จังหวัด/รัฐ |
ขอนแก่น |
ช่วงวันที่จัดประชุม |
8 กรกฎาคม 2562 |
ถึง |
10 กรกฎาคม 2562 |
Proceeding Paper |
Volume (ปีที่) |
17 |
Issue (เล่มที่) |
1 |
หน้าที่พิมพ์ |
348-354 |
Editors/edition/publisher |
Assoc. Prof. Jarin Paphangkorakit |
บทคัดย่อ |
ABSTRACT
Background: Oral squamous cell carcinoma (OSCC) is the most common cancer in the oral cavity. This malignant
tumor may locally destroy the surrounding tissue, such as the gingiva and jaw bones, and later spread to some
regional lymph nodes and other distant organs. Bone invasion by OSCC has major effects on tumor staging,
outcome and quality of life. Various types of radiograph have been used as important diagnostic tools to detect tumor invasion both in the bone and soft tissue, including cervical lymph nodes. More than 50% of head and neck squamous cell carcinoma patients present with regional lymph node involvement. Lymph node metastasis is
associated with poor survival and is one of the most important factors for selecting appropriate treatment. In Thailand, although many advanced radiographic techniques are available in some referral medical centers, panoramic
radiography is still the most commonly used technique for screening bone invasion because of its many advantages. However, there are still some questions whether the detection of bone invasion by the tumor using panoramic radiography can have a benefit of predicting cervical lymph node metastasis or not.
Objectives: This study aimed to preliminarily investigate the association of bone invasion by tumor and cervical
lymph node metastasis by comparing patient pre-operative panoramic radiographs and
histopathologic evidence of cervical lymph node metastasis.
Methods: Panoramic radiographs of seventy-five patients who had OSCC treated by surgical resection and modified
or radical neck dissection were retrieved and analyzed by using Fisher’s exact test. P<0.05 was considered
statistically significant. All the cervical lymph nodes taken from the modified or radical neck dissection were
histologically examined to provide information of cervical lymph node metastasis.
Results: The Fisher’s exact test of bone invasion and cervical lymph node metastasis was 0.812. No statistically
significant correlation was observed.
Conclusion: We concluded that panoramic radiography should be used only as an initial imaging for screening
bone invasion in OSCC because of the lower sensitivity compared with other techniques. The result of our study
also demonstrated that there was no statistically significant correlation between bone invasion and cervical lymph node metastasis. Therefore, more advanced imaging techniques are needed as an adjunct tool for detecting bone
invasion and cervical lymph node metastasis of oral cancer.
Keywords: Advanced imaging, Bone invasion, Cervical lymph node metastasis, Oral squamous cell carcinoma, Panoramic radiograph |
ผู้เขียน |
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การประเมินบทความ (Peer Review) |
มีผู้ประเมินอิสระ |
มีการเผยแพร่ในระดับ |
นานาชาติ |
รูปแบบ Proceeding |
Full paper |
รูปแบบการนำเสนอ |
Poster |
เป็นส่วนหนึ่งของวิทยานิพนธ์ |
เป็น |
ผลงานที่นำเสนอได้รับรางวัล |
ไม่ได้รับรางวัล |
แนบไฟล์ |
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Citation |
10
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