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Publication
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Title of Article |
Atalantums H-K from the peels of Atalantia monophylla and their cytotoxicity |
Date of Acceptance |
26 January 2019 |
Journal |
Title of Journal |
NATURAL PRODUCT RESEARCH |
Standard |
ISI |
Institute of Journal |
Informa UK Limited, trading as Taylor & Francis Group |
ISBN/ISSN |
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Volume |
2019 |
Issue |
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Month |
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Year of Publication |
2019 |
Page |
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Abstract |
Four new benzoyltyramines, atalantums H-K (1-4) were isolated from the peels of Atalantia monophylla. All compounds were tested for cytotoxicity against HeLa, HCT116 and MCF-7 cell lines, as well as normal cells (Vero cells). Compound 5 showed cytotoxicity against HeLa, HCT116 and MCF-7 cell lines with IC50 values ranging from 16-25 ug/mL but was inactive against Vero cells. Compound 6 also showed interesting results as compound 5 with IC50 values ranging from 15-18 g/mL and an IC50 value of 80.20 ug/mL against Vero cells. This means compounds 5 and 6 can be used as lead compounds for anticancer agents. |
Keyword |
Atalantia monophylla, atalantum, benzoyltyramine |
Author |
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Reviewing Status |
มีผู้ประเมินอิสระ |
Status |
ตีพิมพ์แล้ว |
Level of Publication |
นานาชาติ |
citation |
true |
Part of thesis |
true |
Attach file |
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Citation |
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