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Publication
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| Title of Article |
A new flavonoid from the leaves of Atalantiamonophylla (L.) DC |
| Date of Acceptance |
21 March 2018 |
| Journal |
| Title of Journal |
Natural Product Research |
| Standard |
ISI |
| Institute of Journal |
Taylor and Francis Online |
| ISBN/ISSN |
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| Volume |
33 |
| Issue |
8 |
| Month |
March |
| Year of Publication |
2021 |
| Page |
1115-1121 |
| Abstract |
A new flavonoid, atalantraflavone (1) as well as eight known compounds including atalantoflavone (2), racemoflavone (3), 5,4′-dihydroxy-(3″,4″-dihydro-3″,4″-dihydroxy)-2″,2″-dimethylpyrano-(5″,6″:7,8)-flavone (4), lupalbigenin (5), anabellamide (6), citrusinine I (7), p-hydroxybenzaldehyde (8), and frideline (9), were isolated from the leaves of Atalantia monophylla (L.) DC. Focusing on Alzheimer’s disease, acetylcholine esterase (AChE) inhibition and antioxidant activity were evaluated using the modified Ellman’s method and the ABTS scavenging assay, respectively. It was found that isoflavonoid 5, lupalbigenin, showed 79% inhibition to AChE and was 1.4-fold stronger than the tacrine standard. In addition, acridone 7, citrusinine I, displayed 90.68% antioxidant activity. |
| Keyword |
Atalanta monophylla, flavonoid, acetylcholine esterase, antioxidant |
| Author |
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| Reviewing Status |
มีผู้ประเมินอิสระ |
| Status |
ตีพิมพ์แล้ว |
| Level of Publication |
นานาชาติ |
| citation |
true |
| Part of thesis |
true |
| Attach file |
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| Citation |
0
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Journal Publication
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