| Research Title |
ANTI-INFLAMMATORY ACTIVITY OF THE ETHANOLIC EXTRACT OF THE POWDER FORMULA OF A FUNGUS Cordyceps sinensis AND THREE HERBS (Panax ginseng, Kaempferia parviflora AND Houttuynia cordata) IN RAW264.7 CELLS |
| Date of Distribution |
6 October 2021 |
| Conference |
| Title of the Conference |
The 47th International Congress on Science, Technology and Technology-based Innovation (STT47) “Sciences for SDGs: Challenges and Solutions” |
| Organiser |
The Science Society of Thailand under the Patronage of His Majesty the King in Association with Faculty of Liberal Arts and Science, Kasetsart University, Kamphaeng Saen Campus |
| Conference Place |
Kasetsart University, Kamphaeng Saen Campus |
| Province/State |
Nakhon Pathom, Thailand (Zoom, Virtual Conference) |
| Conference Date |
5 October 2021 |
| To |
7 October 2021 |
| Proceeding Paper |
| Volume |
47 |
| Issue |
1 |
| Page |
310-317 |
| Editors/edition/publisher |
|
| Abstract |
The powder formula of a fungus Cordyceps sinensis and three herbs (Panax ginseng, Kaempferia parviflora and Houttuynia cordata) (PFCPKH) was developed as a dietary supplement to enhance health. In this research, the anti-inflammatory activity of ethanolic extract of PFCPKH was studied in RAW264.7 cells. The cell viability remained above 90% until a concentration of 60 µg/mL. The concentrations of ethanolic extract of PFCPKH used for studying the anti-inflammatory activity were 10-60 µg/mL. All these concentrations exhibited anti-inflammatory activity as the nitric oxide (NO) and prostaglandin E2 (PGE2) productions in RAW264.7 cells were significantly decreased (p < 0.05) when compared with lipopolysaccharide (LPS) alone treatment. The identified phenolic compounds of PFCPKH ethanolic extract including p-Hydroxybenzoic acid, Vanillic acid, Syringic acid, p-Coumaric acid, Ferulic acid and Sinapinic acid. The results demonstrated for the first time the anti-inflammatory activity of the industrialized PFCPKH in vitro, thus validating its promising anti-inflammation potential. |
| Author |
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| Peer Review Status |
มีผู้ประเมินอิสระ |
| Level of Conference |
นานาชาติ |
| Type of Proceeding |
Full paper |
| Type of Presentation |
Oral |
| Part of thesis |
true |
| Presentation awarding |
false |
| Attach file |
|
| Citation |
0
|
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Publication
Journal Publication
ไทย