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Publication
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| Title of Article |
Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract |
| Date of Acceptance |
7 April 2022 |
| Journal |
| Title of Journal |
Journal of Cosmetic Dermatology |
| Standard |
SCOPUS |
| Institute of Journal |
WILEY |
| ISBN/ISSN |
https://doi.org/10.1111/jocd.14982 |
| Volume |
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| Issue |
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| Month |
April |
| Year of Publication |
2022 |
| Page |
1-13 |
| Abstract |
Background: Asian skin undergoing chronological aging, accumulates signs of photoaging
mediated by prolonged exposure to ultraviolet (UV) radiation. Although sunscreens are
effective in preventing signs of photoaging, polyphenol-rich extracts e.g., grape seed extract
(GSE) can provide additional protection through the broad spectrum of biological activities.
Aims: To access the effectiveness of a sunscreen formulation containing GSE as an important
cosmetic ingredient for the improvement of age-related changes in Asian skin using
noninvasive evaluation techniques.
Methods: Noninvasive methods were used to assess changes in the biophysical properties
corresponding to aging signs including melanin and erythema indices, color parameters of the
CIE L*a*b* system, elasticity, and hydration of the forearm skin before and after applying the
sunscreen with GSE. In addition, to confirm the effectiveness of the tested product, we
compared it with benchmark sunscreen, and a cream base containing either GSE or UV filters.
Results: Twice-daily application of sunscreen containing 3% GSE significantly reduced the
level of melanin and erythema and improved overall skin tone. The hydration was drastically
increased after 3 hours of wearing formulation and was maintained relatively high for 5 hours.
Skin elasticity parameters, including Young’s modulus, retraction time, and viscoelasticity
improved in participants of all age categories (35-59 years). Moreover, sunscreen with GSE,
as acclaimed by participants, improved overall skin appearance.
Conclusions: The balancing potential of GSE on the skin, combined with the photoprotective
properties of UV filters demonstrated an added value as an anti-aging agent and proved
efficacy for both photoaged and chronologically aged Asian skin. |
| Keyword |
grape seed extract, sunscreen, anti-aging, melanin, erythema, hydration, elasticity |
| Author |
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| Reviewing Status |
ไม่มีผู้ประเมินอิสระ |
| Status |
ตีพิมพ์แล้ว |
| Level of Publication |
นานาชาติ |
| citation |
false |
| Part of thesis |
true |
| Attach file |
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| Citation |
0
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Journal Publication
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