2012 ©
             Publication
Journal Publication
Title of Article Meta-analysis for evaluating the effect of prebiotics supplementation on microbiota diversity indices in chicken intestine 
Date of Acceptance 30 December 2021 
Journal
     Title of Journal สัตวแพทยศาสต์ มข. 
     Standard TCI 
     Institute of Journal คณะสัตวแพทยศาสตร์ มหาวิทยาลัยขอนแก่น 
     ISBN/ISSN 0858-2297 
     Volume 31 
     Issue
     Month ธันวาคม
     Year of Publication 2021 
     Page 69-84 
     Abstract Objective: To evaluate the effect of prebiotics supplementation on microbiota diversity indices in chicken intestine.Materials and Methods: Relevant citations were retrieved from PubMed, Scopus and Web of Science databases. The titles and abstracts of the retrieved citations were preliminary screened for their eligibility. Then, full-text articles were assessed using in-depth screening from the methodology and the result sections of the articles for inclusion. Data of the included studies were extracted for further analysis. Risk of bias of the included studies was also assessed using SYRCLE’s risk of bias tool. A meta-analysis was performed with a random effects model. The study outcomes were standardized mean difference (SMD) of Shannon index, Simpson index and Chao1. The pooled estimates of the effect size of prebiotic supplementation on microbiota diversity of chicken intestine were determined. In addition, sensitivity analysis, and assessment for publication bias were conducted. Results: Prebiotic supplementation significantly increased the Shannon index (SMD=1.01, [95% CI, 0.33 to 1.68], P=0.003), but not significantly altered Simpson index (SMD=0.78, [95% CI, -0.24 to 1.79], P=0.133) and Chao1 (SMD=-0.07, [95% CI, -0.35 to 0.21], P=0.633), with high heterogeneity. Sensitivity analysis indicated that the Simpson index was not robust for all three assessed characteristics, whereas publication bias assessment showed some bias in Chao1 outcome.Conclusion: Prebiotic supplementation tends to increase Shannon index in chicken intestine; however, more relevant trials are required to confirm the results. 
     Keyword Meta-analysis, prebiotic, diversity index, microbiota, chicken 
Author
597180003-2 Miss KANLAYA WORAWONG [Main Author]
Veterinary Medicine Doctoral Degree

Reviewing Status มีผู้ประเมินอิสระ 
Status ตีพิมพ์แล้ว 
Level of Publication ชาติ 
citation true 
Part of thesis true 
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