2012 ©
             Publication
Journal Publication
Title of Article Intermittent hypoxic exposure with or without exercise improved cardiopulmonary functions in people with cardiovascular risk factors. 
Date of Acceptance 14 May 2023 
Journal
     Title of Journal Asia-Pacific Journal of Science and Technology (APST) 
     Standard TCI 
     Institute of Journal Universities and Research Institutions in Thailand 
     ISBN/ISSN 25396293 
     Volume 28 
     Issue
     Month June
     Year of Publication 2023 
     Page  
     Abstract This research aimed to explore the effects of intermittent hypoxic exposure (IH) with or without exercise on lung function, body composition, lipid profile, haematological variables, and a 6-min walk in people with three cardiovascular risk factors (hypertension stage I, hyperlipidemia, and obesity). Thirty participants were randomly allocated into 3 groups: a control group (CON, n=11) received no training, an intermittent hypoxic exposure during rest group (IHR, n=9), and an intermittent hypoxic training group (IHT, n=10) who combined IH with walking on a motorized treadmill. Both IHR and IHT performed 8 sessions of 3-min of hypoxic breathing (14% O2) alternated with 3-min of normoxic breathing (21% O2) for 48-min per day, twice a week, for 6 consecutive weeks. All participants were measured before and after 6 weeks of the experimental period. After training, IHR group significantly increased vital capacity (p=0.038) and forced vital capacity (p=0.025) compared to baseline. Similarly, compared to baseline, participants in the IHT group revealed significantly increased vital capacity (p=0.030), forced vital capacity (p=0.031), and forced expiratory volume in 1 second (p=0.042). Compared to CON, only IHT showed a significant increase in forced vital capacity of 8.6 ± 4.5% (p=0.034) and forced expiratory volume in 1 second of 7.0 ± 3.9%, (p=0.033) after 6 weeks. Both the IHR and IHT participants demonstrated a significantly increased 6-minute walk distance (p=0.048 and p=0.004, respectively) compared to CON. The study demonstrated that IH programs can improve lung function and cardio-pulmonary fitness which indicates that IH with or without exercise improves some cardiopulmonary functions in at risk patients.  
     Keyword Hypoxic training, lung function, vital capacity body mass index, six-minute walk distance 
Author
607070026-4 Miss WISUTTHIDA SAENGJAN [Main Author]
Medicine Doctoral Degree

Reviewing Status มีผู้ประเมินอิสระ 
Status ได้รับการตอบรับให้ตีพิมพ์ 
Level of Publication ชาติ 
citation false 
Part of thesis true 
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